Results 41 to 50 of about 1,387,037 (263)
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Study region: This study spans the Prairie/parkland/boreal transition in central Alberta, including lakes in the Athabasca, North Saskatchewan, Battle River and Red Deer Basins.
J.J. Gibson +4 more
doaj +1 more source
Spatial distribution of oxygen-18 and deuterium in stream waters across the Japanese archipelago [PDF]
The spatial distribution of oxygen and hydrogen isotopic composition (δ18O and δ2H) of stream waters across Japan was clarified with a data set by compiling sample data obtained from 1278 forest catchments during the summer of 2003.
M. Katsuyama, T. Yoshioka, E. Konohira
doaj +1 more source
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Hydrochemical and isotope groundwater investigations in Sorško polje
From the hydrogeological point of view Sorško polje area is a sink, filled with conglomerate,sandand gravel,where large quantities of groundwater are accumulated.
Brigita Jamnik, Janko Urbanc
doaj
Planetary fertility during the past 400 ka based on the triple isotope composition of O2 in trapped gases from the Vostok ice core [PDF]
The productivity of the biosphere leaves its imprint on the isotopic composition of atmospheric oxygen. Ultimately, atmospheric oxygen, through photosynthesis, originates from seawater.
J. C. von Fischer +3 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Príspevok syntetizuje dostupné údaje o izotopickom zložení zrážok na území Slovenska (Západné Karpaty). Hodnotí koreláciu hodnôt δ18O v kumulatívnych mesačných zrážkach z rokov 1988-1997 medzi jednotlivými stanicami, vplyv nadmorskej výšky, teploty ...
Holko Ladislav +3 more
doaj +1 more source
Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source

