Results 61 to 70 of about 247,613 (312)

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

Feasibility Study of an Iron-Based Composite Added with Al₂O₃/ZrO₂ as an Oxygen Carrier in the Chemical Looping Applications

Crystals, 2021
The chemical looping process is a promising approach for carbon capture. Oxygen carriers play the crucial role of carrying oxygen between oxidation and reduction reactors.
Ching-Ti Kao, Cheng-Hsien Shen, Heng-Wen Hsu   +2 more
doaj   +1 more source

A PEGylated bovine hemoglobin as a potent hemoglobin-based oxygen carrier

, 2017
Hemoglobin (Hb)-based oxygen carriers (HBOCs) have been used as blood substitutes in surgery medicine and oxygen therapeutics for ischemic stroke.
Hu, Tao, You, Guoxing, Li, Penglong, Dawei Gao, Wang, Ying, Penglong Li, Tao Hu, Hong Zhou, Wang, Linli, Weili Yu, Zhang, Shan, Linli Wang, Jun Zhang, Yu, Weili, Shan Zhang, Ying Wang, Lian Zhao, Zhao, Lian, Zhou, Hong, Guoxing You, Gao, Dawei, Zhang, Jun   +21 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Computational Fluid Dynamics Study of a Complete Coal Direct Chemical Looping Sub-Pilot Unit [PDF]

Iranian Journal of Chemistry & Chemical Engineering, 2016
The present Computational Fluid Dynamics (CFD) work deals with the modeling of complete coal direct chemical looping sub-pilot unit which use coal as fuel and ferric oxide supported on alumina as an oxygen carrier.
Rahul Wadhwani, Bikash Mohanty
doaj  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

High-Quality Syngas Production by Chemical Looping Gasification of Bituminite Based on NiFe₂O₄ Oxygen Carrier

Energies, 2023
Chemical looping gasification (CLG) is an effective coal utilization technology. In this work, the CLG of bituminite was investigated through fixed-bed batch experiments using NiFe2O4 oxygen carrier (OC) to achieve high-quality syngas. The changes in the
Ming Yang, Da Song, Yang Li, Jinzeng Cao, Guoqiang Wei, Fang He   +5 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Improving CO₂ Capture Efficiency Through Novel CLOU-Based Fuel Reactor Configuration in Chemical Looping Combustion

Energies
Climate change and global decarbonization targets drive the search for more efficient and cost-effective combustion technologies. Chemical looping combustion (CLC) using solid oxygen carriers with chemical looping with oxygen uncoupling (CLOU ...
Anna Zylka, Jaroslaw Krzywanski, Tomasz Czakiert, Marcin Sosnowski, Karolina Grabowska, Dorian Skrobek, Lukasz Lasek   +6 more
doaj   +1 more source