Results 71 to 80 of about 4,474,605 (404)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Diffusion and Monod kinetics model to determine in vivo human corneal oxygen-consumption rate during soft contact lens wear

Journal of Optometry, 2015
Purpose: We present an analysis of the corneal oxygen consumption Qc from non-linear models, using data of oxygen partial pressure or tension (pO2) obtained from in vivo estimation previously reported by other authors.1 Methods: Assuming that the cornea ...
Luis F. Del Castillo, Ana R. Ferreira da Silva, Saul I. Hernández, M. Aguilella, Andreu Andrio, Sergio Mollá, Vicente Compañ   +6 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Effects of macrobenthos on sediment-water oxygen and ammonium fluxes. Final Report. [PDF]

, 1997
Sediments are an important location in determining the fate of nutrients entering the estuary. Role of sediments needs to be incorporated into water quality models.
Barnes, J.M., Boynton, Walter R., Magdeburger, L.L., Weaver, B.J.   +3 more
core  

PON2 Deficiency Leads to Increased Susceptibility to Diet-Induced Obesity. [PDF]

, 2019
(1) Background: Paraoxonase 2 (PON2) is a ubiquitously expressed protein localized to endoplasmic reticulum and mitochondria. Previous studies have shown that PON2 exhibits anti-oxidant and anti-inflammatory functions, and PON2-deficient (PON2-def) mice ...
Fogelman, Alan M, Lusis, Aldons J, Meng, Yonghong, Reddy, Srinivasa T, Reue, Karen, Sallam, Tamer, Shih, Diana M, Shu, Michelle L, Tontonoz, Peter, Vergnes, Laurent   +9 more
core   +1 more source

Microfluidic electro‐viscoelastic manipulation of extracellular vesicles

FEBS Open Bio, EarlyView.
The electro‐viscoelastic manipulation as a potential method for separation of particles based on size. The particles introduced as a sheath flow migrate to the channel center under the influence of simultaneously applied electric field and pressure driven flow.
Seyedamirhosein Abdorahimzadeh, Éva Bozó, Zikrullah Bölükkaya, Artem Zhyvolozhnyi, Anatoliy Samoylenko, Henrikki Liimatainen, Seppo J. Vainio, Caglar Elbuken   +7 more
wiley   +1 more source

Relationship between oxygen consumption kinetics and BODE Index in COPD patients

International Journal of COPD, 2012
Audrey Borghi-Silva,1 Thomas Beltrame,1,2 Michel Silva Reis,1 Luciana Maria Malosá Sampaio,3 Aparecida Maria Catai,1 Ross Arena,4 Dirceu Costa31Cardiopulmonary Physiotherapy Laboratory, Nucleus of Research in Physical Exercise, Federal ...
Borghi-Silva A, Beltrame T, Reis MS, Sampaio LM, Catai AM, Arena R, Costa D   +6 more
doaj  

Regulation of benthic oxygen fluxes in permeable sediments of the coastal ocean [PDF]

, 2017
Large areas of the oceanic shelf are composed of sandy sediments through which reactive solutes are transported via porewater advection fueling active microbial communities.
Ahmerkamp, Soeren, Beer, Dirk de, Friedrich, Jana, Holtappels, Moritz, Janssen, Felix, Krämer, Knut, Kuypers, Marcel M. M., Winter, Christian   +7 more
core   +1 more source

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

FEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić, Darija Putar, Lucija Mijanović, Igor Weber   +3 more
wiley   +1 more source

A practical guide for the analysis, standardization and interpretation of oxygen consumption measurements

Nature Metabolism, 2022
Ajit S. Divakaruni, M. Jastroch
semanticscholar   +1 more source