Results 71 to 80 of about 8,048,898 (290)

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Changes of oxygen consumption rates in response to various environmental factors and different anesthetic methods in juvenile hybrid sturgeon, Acipenser baeri♀×Acipenser schrencki♂

Aquaculture Reports
Live fish transportation plays a crucial role in realizing the value of aquaculture in sturgeons. However, hypoxia and hypercapnia are the major issues during the high-density transportation of live fish.
Baoliang Bi, Songpei Zhang, Yin Yuan, Fuquan Zhang, Yu Gao   +4 more
doaj   +1 more source

Sensitivity Analysis and Optimization of Operating Parameters of an Oxyfuel Combustion Power Generation System Based on Single-Factor and Orthogonal Design Methods

Energies, 2020
The main purpose of this paper is to quantitatively analyze the sensitivity of operating parameters of the system to the thermodynamic performance of an oxyfuel combustion (OC) power generation system.
Zhiyu Zhang, Rongrong Zhai, Xinwei Wang, Yongping Yang   +3 more
doaj   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Accelerometer Derived Activity Counts and Oxygen Consumption between Young and Older Individuals

Journal of Aging Research, 2014
The purpose of this investigation was to compare accelerometer activity counts and oxygen consumption between young and elderly individuals. Sixteen young (21.3±2.5 yrs) and sixteen elderly (66.6±2.9 yrs) participants completed 30 minutes of resting ...
Lucas Whitcher, Charilaos Papadopoulos
doaj   +1 more source

Fluorination: A strategy to tune the interactions of molecules and nanoscale systems with biological matter

FEBS Open Bio, EarlyView.
This minireview explores fluorination as a key strategy to optimize therapeutic molecules and nanocarriers. By incorporating different fluorinated motifs—from single atoms to linear and branched chains—drug delivery, cellular uptake, and colloidal stability can be improved and fine‐tuned.
Martina Beccalli, Beatrice Lucia Bona, Francesca Baldelli Bombelli   +2 more
wiley   +1 more source

Understanding and Mitigating the Risk of Accelerated Biological Aging in Survivors of Cancer: A Scoping Review

Aging and Cancer, EarlyView.
Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi, Emily Herdman, Danielle Westmark, Vijaya R. Bhatt   +3 more
wiley   +1 more source

Characteristics of study participants and heart rate and oxygen consumption during rest and peak oxygen consumption.

, 2019
Characteristics of study participants and heart rate and oxygen consumption during rest and peak oxygen consumption.
Tobias Holmlund (8072258), Claes Hultling (5393972), Elin Ekblom-Bak (738186), Kerstin Wahman (5393966), Erika Franzén (791309)   +4 more
core   +1 more source

Oxygen Consumption Rate of Polychaeta Nereis sp. Different Sizes and Type of Feed

Ilmu Kelautan, 2019
Nereis  sp. contains amino acids and unsaturated fatty acids that can improve the quality of gamete stem cells and the quality of the resulting larvae. Nereis  sp. can increase gamete cell maturation in the parent shrimp up to 70%.
Eko Setio Wibowo, Endah Sri Palupi, I G A Ayu Ratna Puspitasari, Atang Atang   +3 more
doaj   +1 more source