Results 51 to 60 of about 1,065,517 (297)
Nano-Micro Letters, 2020 Rheumatoid arthritis (RA) is an autoimmune disease, which attacks human joint system and causes lifelong inflammatory condition. To date, no cure is available for RA and even the ratio of achieving remission is very low. Hence, to enhance the efficacy of
Xing-xing Fan +5 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Microcirculation and Macrocirculation in Cardiac Surgical Patients
Critical Care Research and Practice, 2012 Background. The aim of our study was to investigate the relationship between microcirculatory alterations after open cardiac surgery, macrohemodynamics, and global indices of organ perfusion. Methods.
Elli-Sophia Tripodaki +8 more
doaj +1 more source
Oxygen Consumption Characteristics in 3D Constructs Depend on Cell Density
Frontiers in Bioengineering and Biotechnology, 2019 Oxygen is not only crucial for cell survival but also a determinant for cell fate and function. However, the supply of oxygen and other nutrients as well as the removal of toxic waste products often limit cell viability in 3-dimensional (3D) engineered ...
C. Magliaro +5 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
The Effects of Compression Pants on Oxygen Consumption and Heart Rate during Long-Distance Running
BiomechanicsThe purpose of this study was to compare average rate of oxygen consumption (VO2), slow component of oxygen consumption (VO2 drift), heart rate (HR) and rating of perceived exertion (RPE) while wearing compression pants vs.
Andrew Craig-Jones +4 more
doaj +1 more source
Спортивная медицина: наука и практика, 2020 Objective: the purpose of the study was to evaluate how high-intensity interval training affects strength, oxidative capacity and hypertrophy of working muscles in power sports athletes.
A. B. Miroshnikov +2 more
doaj +1 more source
FEBS Open Bio, EarlyView.This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake +4 more
wiley +1 more source
Acute caffeine treatment protects the developing retina from ischemia‐induced cell death
FEBS Open Bio, EarlyView.Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento +6 more
wiley +1 more source
Journal of Optometry, 2015 Purpose: We present an analysis of the corneal oxygen consumption Qc from non-linear models, using data of oxygen partial pressure or tension (pO2) obtained from in vivo estimation previously reported by other authors.1 Methods: Assuming that the cornea ...
Luis F. Del Castillo +6 more
doaj +1 more source