Results 121 to 130 of about 57,040 (314)

Local vasoregulative interventions impact drug concentrations in the skin after topical laser‐assisted delivery

open access: yesLasers in Surgery and Medicine, Volume 54, Issue 10, Page 1288-1297, December 2022., 2022
Abstract Introduction The ability of ablative fractional lasers (AFL) to enhance topical drug uptake is well established. After AFL delivery, however, drug clearance by local vasculature is poorly understood. Modifications in vascular clearance may enhance AFL‐assisted drug concentrations and prolong drug dwell time in the skin.
Emily Wenande   +8 more
wiley   +1 more source

Respiratory Inhaler Sound Event Classification Using Self-Supervised Learning [PDF]

open access: yesarXiv
Asthma is a chronic respiratory condition that affects millions of people worldwide. While this condition can be managed by administering controller medications through handheld inhalers, clinical studies have shown low adherence to the correct inhaler usage technique.
arxiv  

Simulation study of dose enhancement in a cell due to nearby carbon and oxygen in particle radiotherapy [PDF]

open access: yesarXiv, 2015
The aim of this study is to investigate the dose-deposition enhancement by alpha-particle irradiation in a cellular model using carbon and oxygen chemical compositions.A simulation study was performed to study dose enhancement due to carbon and oxygen for a human cell where Geant4 code used for the alpha-particle irradiation to the cellular phantom ...
arxiv  

Evaluation study of inhaled oxygen concentration with combined use of ventilator and liquid oxygen in home oxygen therapy

open access: gold, 2023
T. Hishinuma   +6 more
openalex   +2 more sources

Description of unilateral kidney embolism and contralateral nephrectomy as a less invasive remnant kidney model in cats; a proof‐of‐concept study

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Unilateral, minimally invasive, renal arterial embolization and delayed contralateral nephrectomy was described in cats as a novel remnant kidney model of chronic kidney disease using two doses of embolic particles. Renal function declined and characteristic histopathological markers of kidney disease were present 6 months after the embolism procedure.
Chad W. Schmiedt   +7 more
wiley   +1 more source

The Comprehensive Roadmap Toward Malaria Elimination Using Graphene and its Promising 2D Analogs

open access: yesAdvanced NanoBiomed Research, EarlyView.
Material based on a diversity of graphene with chemical properties of strong strength, high mobility, high transparency, good heat conductivity, biocompatibility, and chemical stability, advanced devices demonstrating antimalarial characteristics can be used for malaria treatment at different stages of malaria development from the injection of ...
Fangzhou He   +11 more
wiley   +1 more source

Hydrophilic Particles Exit While Hydrophobic Particles Persist Following In Vivo Biodegradation of Nanoparticle‐Laden Polymeric Devices

open access: yesAdvanced NanoBiomed Research, EarlyView.
Functionalizing biomedical implants with nanoparticle contrast agents introduces imaging capabilities to devices, improving patient care by avoiding inherent complications. However, nanoparticle surface chemistry optimized for device manufacturing may not lead to efficient nanoparticle clearance from tissues.
Kendell M. Pawelec   +4 more
wiley   +1 more source

Mechanism and Prevention of Hyperbaric Oxygen Convulsions [PDF]

open access: yesarXiv
Hyperbaric oxygen therapy (HBOT) proves vital in saving lives by elevating the partial pressure of oxygen (pO2). However, HBOT may also have toxic effects, including lung and retinal damage (peripheral HBOT toxicity), muscle spasms and violent myoclonic convulsions (CNS HBOT toxicity), which may even lead to death if left untreated.
arxiv  

Review of the anatomical basis for predicting plutonium alpha particle radiation induced osteogenic cancers

open access: yesThe Anatomical Record, EarlyView.
Abstract Plutonium was discovered and first synthesized in the early 1940's. Several isotopes of plutonium are used in nuclear technologies, 238Pu for heat generation and 239Pu for energy production and weapons. Both isotopes emit alpha particles, which pose a significant radiation hazard when incorporated into the body.
Scott C. Miller
wiley   +1 more source

Role of RNA modifications in carcinogenesis and carcinogen damage response

open access: yesMolecular Carcinogenesis, Volume 62, Issue 1, Page 24-37, January 2023., 2023
Abstract The field of epitranscriptomics encompasses the study of post‐transcriptional RNA modifications and their regulatory enzymes. Among the numerous RNA modifications, N6‐methyladenosine (m6A) has been identified as the most common internal modification of messenger RNA (mRNA).
Michelle Verghese   +2 more
wiley   +1 more source

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