Results 121 to 130 of about 86,914 (348)
The Role of Intensive Insulin Therapy on Superoxide Dismutase (Sod), Tumor Necrosis Factor-? (Tnf-?), and Interleukin-6 (Il-6) on Hyperglycemia in Critically Ill Patients [PDF]
, 2009 Hyperglycemia and insulin resistance are common in critically ill patientsin the ICU, although they have not previously had diabetes. It has been reportedthat pronounced hyperglycemia may lead to complications in such patients, andcause the reactive ...
Bagianto, H. (Hari) +3 more
core
Gabpα‐Pparγ Complex Determines Glycolytic Capacity and Lactic Acid Homeostasis in Brown Fat
Advanced Science, EarlyView.This study identifies the Gabpα–Pparγ complex as a key transcriptional regulator that couples glycolysis to lactate‐driven thermogenesis in brown adipose tissue by directly activating Eno1 transcription. Competitive disruption of this interaction impairs lactate metabolism and thermogenic capacity.
Zhihan Wang +22 more
wiley +1 more source
Advanced Science, EarlyView.A multifunctional nano immunostimulant is first proposed for efficient tumor immunotherapy. The ER targeted ability, superior ROS production, efficient GSH consumption, coupled with the HIF suppression, jointly arouses ICD/ferroptosis pathways to realize efficient tumor immunotherapy.
Guanhong Guo +14 more
wiley +1 more source
Zhongguo cuzhong zazhi目的 评估不同供氧方式的高压氧治疗下，发病30 d内卒中术后患者经皮氧分压（transcutaneous oximetry，TcPO2）的变化。 方法 回顾性纳入2023年1月1日—2024年6月20日在高压氧科接受治疗的发病30 d内卒中术后患者，根据气道情况分为正常气道面罩加储气囊供氧（面罩组）和人工气道头罩供氧（头罩组）。高压氧治疗期间实时监测TcPO2，比较两种供氧方式下TcPO2变化。 结果 本研究共入选26例患者，面罩组和头罩组各13例。面罩组升压开始时TcPO2为（55.92±9.58）
任梓齐1，王勤芳1，2，刘亚玲1，王丛1，于秋红1 (REN Ziqi1, WANG Qinfang1,2, LIU Yaling1, WANG Cong1, YU Qiuhong1 )
doaj +1 more source
Long-acting inhaled anticholinergic therapy improves sleeping oxygen saturation in COPD [PDF]
, 2004 Walter T. McNicholas +3 more
openalex +1 more source
Advanced Science, EarlyView.Schematic model showing the suggested mechanism that ZA induces classical activation of macrophages by impairing mitochondrial biofunction and inhibiting mitochondrial clearance to contribute to the pathological process of BRONJ. RAPA‐loaded nanoparticles ZDPR has shown potential in alleviating BRONJ lesions as well as treating osteoporosis or ...
Hang Zhang +10 more
wiley +1 more source
Oxygen inhalation therapy among elderly patients of a public hospital
, 2022 Mariana Colombini Buranello +2 more
openalex +1 more source
Endothelial Cell‐Based Vascular Bandages for Blood–Brain Barrier Repair and Targeted siRNA Delivery
Advanced Science, EarlyView.mECs restore blood–brain barrier function after cerebral ischemia–reperfusion by simultaneously targeting, supporting, and regulating the damaged vasculature. mECs home to injured cerebral vessels through interactions with highly expressed VLA‐4, reinforce endothelial integrity by forming new junctions, and, upon OGD‐SN treatment, acquire enhanced ...
Yaosheng Li +23 more
wiley +1 more source
The Evolving Pharmacotherapeutic Landscape for the Treatment of Sickle Cell Disease. [PDF]
, 2020 Sickle cell disease (SCD) is an extremely heterogeneous disease that has been associated with global morbidity and early mortality. More effective and inexpensive therapies are needed.
Ballas, Samir K
core +1 more source