Results 61 to 70 of about 187,990 (300)

A case of welder's pneumoconiosis treated with corticosteroid followed by nintedanib

open access: yesRespiratory Medicine Case Reports, 2022
A 32-year-old man who had worked as a welder for 13 years was hospitalized for a fever and hemosputum with dyspnea. He was diagnosed with welding fume-associated lung disease with alveolar hemorrhaging and acute respiratory failure. Despite surviving the
Hideyuki Kaida   +8 more
doaj  

Gasotransmitters in Modern Medicine: Promises and Challenges in the Use of Porous Crystalline Carriers

open access: yesAdvanced Healthcare Materials, EarlyView.
This perspective provides an overview of the growing interest in utilizing various gasotransmitters—small gaseous signaling molecules namely nitric oxide (NO), carbon monoxide (CO), and hydrogen sulfide (H2S)—for several therapeutic applications, with emphasis on the potential use of porous materials as carriers to provide safe and controlled local ...
Rosana V. Pinto   +2 more
wiley   +1 more source

Interstitial N‐Strengthened Copper‐Based Bioactive Conductive Dressings Combined with Electromagnetic Fields for Enhanced Wound Healing

open access: yesAdvanced Healthcare Materials, EarlyView.
This study developed a nitrogen‐strengthened copper‐iron‐zinc (N‐CuFeZn) alloy bioactive dressing integrated with electromagnetic stimulation. The coaxial dressing, made from 0.04 mm filaments with 1120 MPa tensile strength, showed that electromagnetic activation enhanced therapeutic outcomes by increasing VEGF expression, promoting angiogenesis (2.1 ...
Xiaohui Qiu   +9 more
wiley   +1 more source

Inhalability and Bioactivity of Spray‐Dried versus Pressurized Gas eXpanded Liquid Technology‐Processed Yeast Beta‐Glucan Microparticles for Anti‐Fibrotic Therapies

open access: yesAdvanced Healthcare Materials, EarlyView.
PGXTEC) liquid technology is utilized to develop highly respirable yeast beta‐glucan (YBG) microparticles for the treatment of pulmonary fibrosis. Compared to conventionally processed spray‐dried YBG, PGXTEC‐YBG exhibits greatly improved aerodynamic properties, enhanced pro‐fibrotic macrophage uptake, and effective downregulation of pro‐fibrotic ...
Nate Dowdall   +14 more
wiley   +1 more source

Advanced Nanoparticle Therapeutics for Targeting Neutrophils in Inflammatory Diseases

open access: yesAdvanced Healthcare Materials, EarlyView.
This review highlights recent advances in nanoparticle‐based strategies to modulate neutrophil activity in inflammatory diseases. By targeting inflammatory neutrophils, NET formation, and neutrophil apoptosis or recruitment, these approaches aim to improve therapeutic precision.
Min Ji Byun   +9 more
wiley   +1 more source

The influence of oxygenotherapy on the hypercapnia in patients with chronic obstructive pulmonary disease [PDF]

open access: yesVojnosanitetski Pregled, 2008
Background/Aim. Oxygen therapy is a necessary therapeutic method in treatment of severe chronic respiratory failure (CRF), especially in phases of acute worsening.
Lazić Zorica   +3 more
doaj   +1 more source

Biocompatible PVDF Nanofibers with Embedded Magnetite Nanodiscs Enable Wireless Magnetoelectric Stimulation in Premotor Cortex

open access: yesAdvanced Healthcare Materials, EarlyView.
Flexible, biocompatible PVDF nanofibers embedded with magnetite nanodiscs enable wireless magnetoelectric neuromodulation. Shape anisotropy of the nanodiscs facilitates magnetostrictive strain transfer under alternating magnetic fields, allowing activation of neurons in vitro and behavioral modulation in vivo, without requiring rigid implants or ...
Lorenzo Signorelli   +11 more
wiley   +1 more source

Development of a Modular Ribonucleoprotein Complex as a General Strategy to Deliver RNAi Therapeutics

open access: yesAdvanced Healthcare Materials, EarlyView.
A modular and customizable RNAi therapeutics delivery platform composed of a pseudosymmetric human RNA binding protein‐siRNA complex (SmiRNP) is developed. By fusing a targeting module and an endosomal escape peptide onto the delivery platform, SmiRNP successfully delivered siRNA to silence the KRAS oncogene in a colorectal carcinoma cell line, leading
Nok Yin Tam   +9 more
wiley   +1 more source

Titration of oxygen therapy in critically ill emergency department patients: a feasibility study

open access: yesBMC Emergency Medicine, 2018
Background Liberal use of oxygen in an emergency situation is common. Today, most health care professionals do not adjust the amount of oxygen given when a saturation of 100% or a PaO2 which exceeds the normal range is reached- which may result in ...
Anna S. M. Dobbe   +3 more
doaj   +1 more source

De Novo Design of Integrin α5β1 Modulating Proteins to Enhance Biomaterial Properties

open access: yesAdvanced Materials, EarlyView.
NeoNectins are de novo‐designed miniproteins that selectively bind and stabilize the extended open form of integrin α5β1. When grafted onto biomaterials including hydrogel and titanium, they promote cell attachment and spreading in vitro and promoting tissue integration and bone growth in animal models, demonstrating broad potential for regenerative ...
Xinru Wang   +25 more
wiley   +1 more source

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