TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao +10 more
wiley +1 more source
Evaluation of Particle Scattering by Oxygen Ion Cyclotron Harmonic Waves in the Inner Magnetosphere
The scattering of charged particles by oxygen ion cyclotron harmonic (OCH) waves in the inner magnetosphere is investigated by evaluating the relevant quasi‐linear diffusion coefficients.
Fei Yao +5 more
doaj +1 more source
High-Temperature Passivation of the Surface of Candidate Materials for MSR by Adding Oxygen Ions to FLiNaK Salt. [PDF]
Karfidov EA +4 more
europepmc +1 more source
Indiana Oxygen Company Opens, 1915
They found a new venture in 1915 when they combined their engineering and sales talents to form Indiana Oxygen Company, the first industrial gas production plant in the state of Indiana, located on S. Harmon Street in Indianapolis.
core
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Ce-doped Gd3(Al,Ga)5O12 (GAGG:Ce) scintillator single crystals were treated by high-pressure annealing using the hot isostatic pressure in an Ar+20%O2 atmosphere (HIP annealing) to improve their scintillation properties. HIP annealing compensates for the
Yuui Yokota +2 more
doaj +1 more source
Adsorbed Oxygen Ions and Oxygen Vacancies: Their Concentration and Distribution in Metal Oxide Chemical Sensors and Influencing Role in Sensitivity and Sensing Mechanisms. [PDF]
Ciftyurek E, Li Z, Schierbaum K.
europepmc +1 more source
Uncovering G Protein‐Coupled Receptors: Novel Targets and Biomarkers for Predicting Glioma Prognosis
ABSTRACT Background Low‐grade gliomas (LGG) exhibit significant heterogeneity and recurrence risk. G protein‐coupled receptors (GPCR) contribute to glioma malignant progression, but their prognostic value remains unclear. This work attempts to formulate a GPCR‐based outcome‐predicting model for LGG. Methods Based on TCGA LGG data, the enrichment scores
Jun Yang +4 more
wiley +1 more source
Effects of low-dose oxygen ions on cardiac function and structure in female C57BL/6J mice. [PDF]
Nemec-Bakk AS +8 more
europepmc +1 more source
Indiana Oxygen Expands Products to Include Specialty Gases
In 1960, the old air separation plant was replaced by new liquid oxygen, nitrogen, argon and CO2 pumping systems. With this change, Indiana Oxygen began producing specialty gases (Spec Gas) and research laboratory-grade high purity blends.Use of this ...
core

