Results 81 to 90 of about 2,017,034 (245)

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

open access: yesFEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao   +10 more
wiley   +1 more source

Evaluation of Particle Scattering by Oxygen Ion Cyclotron Harmonic Waves in the Inner Magnetosphere

open access: yesGeophysical Research Letters
The scattering of charged particles by oxygen ion cyclotron harmonic (OCH) waves in the inner magnetosphere is investigated by evaluating the relevant quasi‐linear diffusion coefficients.
Fei Yao   +5 more
doaj   +1 more source

Indiana Oxygen Company Opens, 1915

open access: yes, 1910
They found a new venture in 1915 when they combined their engineering and sales talents to form Indiana Oxygen Company, the first industrial gas production plant in the state of Indiana, located on S. Harmon Street in Indianapolis.

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Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Improvement of Scintillation Properties for Cedoped Gd3(Ga,Al)5O12 Scintillator Single Crystal by High-Pressure Annealing

open access: yesAdvances in Materials Science and Engineering
Ce-doped Gd3(Al,Ga)5O12 (GAGG:Ce) scintillator single crystals were treated by high-pressure annealing using the hot isostatic pressure in an Ar+20%O2 atmosphere (HIP annealing) to improve their scintillation properties. HIP annealing compensates for the
Yuui Yokota   +2 more
doaj   +1 more source

Uncovering G Protein‐Coupled Receptors: Novel Targets and Biomarkers for Predicting Glioma Prognosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Low‐grade gliomas (LGG) exhibit significant heterogeneity and recurrence risk. G protein‐coupled receptors (GPCR) contribute to glioma malignant progression, but their prognostic value remains unclear. This work attempts to formulate a GPCR‐based outcome‐predicting model for LGG. Methods Based on TCGA LGG data, the enrichment scores
Jun Yang   +4 more
wiley   +1 more source

Effects of low-dose oxygen ions on cardiac function and structure in female C57BL/6J mice. [PDF]

open access: yesLife Sci Space Res (Amst), 2022
Nemec-Bakk AS   +8 more
europepmc   +1 more source

Indiana Oxygen Expands Products to Include Specialty Gases

open access: yes, 1960
In 1960, the old air separation plant was replaced by new liquid oxygen, nitrogen, argon and CO2 pumping systems. With this change, Indiana Oxygen began producing specialty gases (Spec Gas) and research laboratory-grade high purity blends.Use of this ...

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