Results 81 to 90 of about 7,143,446 (406)

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

IGF-1 Increases with Hyperbaric Oxygen Therapy and Promotes Wound Healing in Diabetic Foot Ulcers

Journal of Diabetes Research, 2013
Objectives. To investigate insulin-like growth factor I (IGF-1) levels in response to hyperbaric oxygen therapy (HBOT) for diabetic foot ulcers and to determine whether IGF-1 is a predictive indicator of wound healing in patients with diabetic foot ...
Figen Aydin, Ahmet Kaya, Levent Karapinar, Mert Kumbaraci, Ahmet Imerci, Hasan Karapinar, Cengiz Karakuzu, Mustafa Incesu   +7 more
doaj   +1 more source

Microfluidic electro‐viscoelastic manipulation of extracellular vesicles

FEBS Open Bio, EarlyView.
The electro‐viscoelastic manipulation as a potential method for separation of particles based on size. The particles introduced as a sheath flow migrate to the channel center under the influence of simultaneously applied electric field and pressure driven flow.
Seyedamirhosein Abdorahimzadeh, Éva Bozó, Zikrullah Bölükkaya, Artem Zhyvolozhnyi, Anatoliy Samoylenko, Henrikki Liimatainen, Seppo J. Vainio, Caglar Elbuken   +7 more
wiley   +1 more source

Efficacy of Hyperbaric Oxygen Therapy for Radiation Cystitis—A Local Center Experience

Hong Kong Journal of Emergency Medicine
Introduction Radiation cystitis is a debilitating condition with no standardized management protocol, significantly impairing the quality of life of patients with cancer treated with pelvic radiotherapy. Hyperbaric oxygen therapy (HBOT) is recognized for
W. C. Yu, A. Siu, W. W. Yan, K. B. Tang
doaj   +1 more source

Case report: Consecutive hyperbaric oxygen therapy for delayed post-hypoxic leukoencephalopathy resulting from CHANTER syndrome caused by opioid intoxication

Frontiers in Medicine
Delayed post-hypoxic leukoencephalopathy (DPHL) is a poorly recognized syndrome characterized by neuropsychiatric symptoms following recovery from an acute hypoxic episode.
Naoto Jingami, Naoto Jingami, Naoto Jingami, Kosai Cho, Takayuki Nitta, Miwa Takatani, Katsuya Kobayashi, Ryo Takenaka, Naoko Sugita, Shigeru Ohtsuru, Shigeru Ohtsuru   +10 more
doaj   +1 more source

Adjunctive Hyperbaric Oxygen Therapy in Refractory Crohn’s Disease: An Observational Study [PDF]

, 2021
Marley Ribeiro Feitosa, Rogério Serafim Parra, Vanessa Foresto Machado, Gustavo Nunes Vilar, Jussara C. Aquino, José Joaquim Ribeiro da Rocha, Paulo Gustavo Kotze, Omar Féres   +7 more
openalex   +1 more source

The impact of Hnrnpl deficiency on transcriptional patterns of developing muscle cells

FEBS Open Bio, EarlyView.
We performed nanopore whole‐transcriptome sequencing comparing RNA from Hnrnpl‐knockdown versus control C2C12 myoblasts to investigate the contributions of Hnrnpl to muscle development. Our results indicate that Hnrnpl regulates the expression of genes involved with Notch signaling and skeletal muscle, particularly splicing patterns of specific muscle ...
Hannah R. Littel, Mekala Gunasekaran, Audrey L. Daugherty, Natalya M. Wells, Johnnie Turner, Christine C. Bruels, Christina A. Pacak, Isabelle Draper, Peter B. Kang   +8 more
wiley   +1 more source

The Effectiveness of Hyperbaric Oxygen Therapy in an Established Intracerebral Tumor Model

Bezmiâlem Science, 2015
Objective:Gliomas are the most common brain tumor in adults. Tumor-related endothelial cells are of neoplastic nature and have malignant properties such as proliferation and invasion.
Tolga Turan DÜNDAR, Mehmet Hakan SEYITHANOĞLU, Şefika KORPINAR, Raziye ATAR, Şevket EVRAN   +4 more
doaj   +1 more source

Smoking Related Home Oxygen Burn Injuries: Continued Cause for Alarm [PDF]

, 2016
Background: Home oxygen therapy is a mainstay of treatment for patients with various cardiopulmonary diseases. In spite of warnings against smoking while using home oxygen, many patients sustain burn injuries.
Baker, Mary S., Bosslet, Gabriel T., Carlos, William G., McPherson, Katie A., Sood, Rajiv, Torke, Alexia M.   +5 more
core   +1 more source

Oxygen therapy in patients with retinal artery occlusion: A meta-analysis

PLoS ONE, 2018
Background Oxygen therapy has been widely used for RAO (retinal artery occlusion) patients; however, inconsistent results have been reported. Methods PubMed, Web of Science, EMBASE, Medline (OvidSP), Cochrane, China National Knowledge Infrastructure ...
Xiaodong Wu, Shuangshuang Chen, Shizun Li, Ji Zhang, Di Luan, Shoucai Zhao, Zhaohu Chu, Yang Xu   +7 more
semanticscholar   +1 more source