Results 121 to 130 of about 220,248 (385)

Research progress on traditional Chinese medicine animal models of post‐stroke depression and pathological insights

Animal Models and Experimental Medicine, EarlyView.
Post‐stroke depression (PSD) animal model of traditional Chinese medicine (TCM) combined with disease and syndrome often uses western medicine surgery (including: middle cerebral artery embolization to construct cerebral ischemia, or brain injection of collagenase to construct cerebral hemorrhage) combined with other methods (including: isolation ...
Jielin Wang, Wenlu Ma, Wei Wu, Yujuan Fu, Hui Li   +4 more
wiley   +1 more source

Lignin-degrading enzyme from Phanerochaete chrysosporium: Purification, characterization, and catalytic properties of a unique H(2)O(2)-requiring oxygenase.

Proceedings of the National Academy of Sciences of the United States of America, 1984
An extracellular lignin-degrading enzyme from the basidiomycete Phanerochaete chrysosporium Burdsall was purified to homogeneity by ion-exchange chromatography. The 42,000-dalton ligninase contains one protoheme IX per molecule.
M. Tien, T. Kirk
semanticscholar   +1 more source

Dual Functions of Dietary Rubber Seed Oil Supplementation: Enriching N‐3 Polyunsaturated Fatty Acids and Enhancing Antioxidant Capacity in Pekin Ducks

Animal Research and One Health, EarlyView.
Dietary RSO supplementation improved growth performance, simultaneously enriched n‐3 polyunsaturated fatty acids (n‐3 PUFA), and enhanced antioxidant capacity in Pekin ducks, which suggested that RSO has the potential to be a novel n‐3 PUFA source and an antioxidant for Pekin ducks to generate animal functional foods.
Lei Zhuang, Yongbao Wu, Zitao Zhao, Junting Cao, Yanhong Guo, Zhanyue Wu, Qimeng Wang, Peilong Yang, Sen Wu, Zhiguo Wen, Shuisheng Hou   +10 more
wiley   +1 more source

The Broad Spectrum HDAC Inhibitor PCI-24781 Induces Caspase- and ROS-Dependent Apoptosis and is Synergistic with Bortezomib in Lymphoma [PDF]

, 2008
We investigated the cytotoxicity and biology of the novel broad-spectrum hydroxamic acid-based histone deacetylase inhibitor (HDACi), PCI-24781. PCI-24781 was studied alone and combined with bortezomib in Hodgkin lymphoma (L428) and non-Hodgkin's ...
Andrew Evens, Joseph Buggy, Kevin David, Lauren Mauro, Leo Gordon, Mint Sirisawad, Richard Miller, Savita Bhalla, Sheila Prachand, Sriram Balasubramanian   +9 more
core   +1 more source

Responses of CYP450 dependent system to aliphatic and aromatic hydrocarbons body burden in transplanted mussels from South coast of Portugal [PDF]

, 2011
Mussels Mytilus galloprovincialis were cross-transplanted at South Portugal from a reference site (site 1) to a site more contaminated with hydrocarbon compounds (site 2), and vice versa, in an active biomonitoring (ABM) concept, to assess the ...
Bebianno, Maria João, Ferreira, A. M., Lopes, Belisandra   +2 more
core   +1 more source

New insights into intracellular locations and functions of heme oxygenase-1.

Antioxidants and Redox Signaling, 2014
SIGNIFICANCE Heme oxygenase-1 (HMOX1) plays a critical role in the protection of cells, and the inducible enzyme is implicated in a spectrum of human diseases.
L. Dunn, R. G. Midwinter, J. Ni, H. Hamid, C. Parish, R. Stocker   +5 more
semanticscholar   +1 more source

GDF10 Regulates Iron‐Dependent Lipid Oxidation in Colorectal Cancer Cells Through Interaction With IGF2

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Background: This study aims to identify genes with a high likelihood of genetic variation, significant expression differences, and prognostic implications in colorectal cancer (CRC) patients. The research also seeks to investigate the role and mechanisms of key genes in CRC through the analysis of health information data and a combination of ...
Kaobin Ouyang, Tianying Huang, Dan Xie, Hailin Xiong   +3 more
wiley   +1 more source

Curcumin activates the haem oxygenase-1 gene via regulation of Nrf2 and the antioxidant-responsive element.

Biochemical Journal, 2003
The transcription factor Nrf2, which normally exists in an inactive state as a consequence of binding to a cytoskeleton-associated protein Keap1, can be activated by redox-dependent stimuli.
E. Balogun, M. Hoque, P. Gong, E. Killeen, C. Green, R. Foresti, J. Alam, R. Motterlini   +7 more
semanticscholar   +1 more source

In Vivo Biosynthesis and Direct Incorporation of Non‐Canonical Amino Acids into Proteins

ChemBioChem, Accepted Article.
Autonomous cells are engineered biological systems capable of biosynthesising and directly incorporating non‐canonical amino acids (ncAAs) into proteins. These systems have the potential to extend the applicability of the genetic code to enable large‐scale fermentative production of proteins carrying ncAAs.
Ivana Drienovska, Jan Hendrik Illies, T. Moritz Weber   +2 more
wiley   +1 more source

A Protochlorophyllide (Pchlide) a Oxygenase for Plant Viability

Frontiers in Plant Science, 2019
Higher plants contain a small, 5-member family of Rieske non-heme oxygenases that comprise the inner plastid envelope protein TIC55, phaeophorbide a oxygenasee (PAO), chlorophyllide a oxygenase (CAO), choline monooxygenase, and a 52 kDa protein (PTC52 ...
Steffen Reinbothe, Sandra Bartsch, Claudia Rossig, Manli Yang Davis, Shu Yuan, Christiane Reinbothe, John Gray   +6 more
doaj   +1 more source