Results 151 to 160 of about 175,409 (339)
The Broad Spectrum HDAC Inhibitor PCI-24781 Induces Caspase- and ROS-Dependent Apoptosis and is Synergistic with Bortezomib in Lymphoma [PDF]
, 2008 We investigated the cytotoxicity and biology of the novel broad-spectrum hydroxamic acid-based histone deacetylase inhibitor (HDACi), PCI-24781. PCI-24781 was studied alone and combined with bortezomib in Hodgkin lymphoma (L428) and non-Hodgkin's ...
Andrew Evens +9 more
core +1 more source
An improved assay for bacterial methane mono-oxygenase: some properties of the enzyme from Methylomonas methanica [PDF]
, 1975 John Colby +2 more
openalex +1 more source
Effect of Natural Polyphenols on Breast Cancer Chemoprevention and Treatment
Molecular Nutrition &Food Research, EarlyView.Effect of Natural Polyphenols on Breast Cancer proliferation and progression. ABSTRACT Breast cancer is the most common type of malignancy among women worldwide. Significant achievements have been made in diagnostic tools and cancer treatments in the past decade; however, the complexity and heterogeneity of certain breast cancer subtypes often lead to ...
Marzia Sichetti +4 more
wiley +1 more source
Heme oxygenase 2 is neuroprotective against intracerebral hemorrhage
Neurobiology of Disease, 2006 Recent studies suggest a neuroprotective function for heme oxygenase 2 (HO2) in acute brain injury and ischemia. HO2, the main enzyme to degrade the pro-oxidant heme, was tested for its neuroprotective ability in postnatal neuronal cell cultures and in a
Jian Wang, Hean Zhuang, Sylvain Doré
doaj
Co-metabolism of methyl- and chloro-substituted catechols by an Achromobacter sp. possessing a new meta-cleaving oxygenase [PDF]
, 1970 R. S. Horvath
openalex +1 more source
Molecular Nutrition &Food Research, EarlyView.Metabolites derived from wild blueberry (poly)phenols, such as syringic (SA), vanillic (VA), and isoferulic acids (IA), can modulate lipid metabolism and oxidative stress markers in mature 3T3‐L1 adipocytes treated with free fatty acids (FFAs; oleic/palmitic acid, 750 µM, 2:1 ratio).
Samuele Venturi +5 more
wiley +1 more source
Heme oxygenase inhibition in cancers : possible tools and targets [PDF]
, 2018 Agnieszka Łoboda +4 more
core +1 more source
Induction of liver cell haem oxygenase in iron-overloaded rats [PDF]
, 1979 Nader G. Ibrahim +2 more
openalex +1 more source
The role of gut microbiota‐derived metabolites in neuroinflammation
Neuroprotection, EarlyView.Gut microbiota‐derived metabolites accumulate in the brain, activating or inhibiting microglia and astrocytes, which affects neuroinflammatory progression. The gut microbiota converts the diet into a variety of metabolites, including bile acid, trimethylamine N‑oxide (TMAO), and indole.
Lingjie Mu, Yijie Wang
wiley +1 more source