Results 171 to 180 of about 60,708 (241)

microRNA‐Mediated Regulation of Oxidative Stress in Cardiovascular Diseases

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
ABSTRACT Background Cardiovascular diseases (CVDs) are the leading cause of mortality globally, often linked to oxidative stress. MicroRNAs (miRNAs) have emerged as significant regulators of oxidative stress within the cardiovascular system. Objective This review examines the complex relationship between miRNAs and oxidative stress, clarifying their ...
Sakhavat Abolhasani   +4 more
wiley   +1 more source

Proteomic study on the lymphocytes from pregnant Wistar rat females treated with immunosuppressive regimen

open access: yesClinical and Translational Science, Volume 16, Issue 1, Page 118-127, January 2023., 2023
Abstract Kidney transplantation remains the therapeutic option for patients with end‐stage kidney disease. Current immunosuppressive regimens are efficient in combating acute kidney rejection. However, insights into chronic kidney allograft injury remains limited.
Bartosz Wojciuk   +6 more
wiley   +1 more source

Brain Tumor Characterization Using Multiple MR Parameters From Multi‐Contrast EPI With Keyhole (GE‐SE EPIK) Including Oxygen Extraction Fraction: A Comparison to O‐(2‐[18F]Fluoroethyl)‐L‐Tyrosine (FET) Positron Emission Tomography

open access: yesJournal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Tumor characterization and treatment efficacy are associated with tissue hypoxia. MR‐derived oxygen extraction fraction (OEF) may offer valuable tumor insights but depends on multiple measurement parameters, often requiring multiple sequence acquisitions.
Fabian Küppers   +10 more
wiley   +1 more source

Genetic variation in NFE2L2 is associated with outcome following aneurysmal subarachnoid haemorrhage

open access: yesEuropean Journal of Neurology, Volume 30, Issue 1, Page 116-124, January 2023., 2023
Abstract Background and purpose Nuclear factor erythroid 2‐related factor 2 (NRF2; encoded by the NFE2L2 gene) has been implicated in outcome following aneurysmal subarachnoid haemorrhage (aSAH) through its activity as a regulator of inflammation, oxidative injury and blood breakdown product clearance.
Ben Gaastra   +10 more
wiley   +1 more source

Preservation of stable isotopic composition in charred grains: Implications for paleoenvironmental and archeological research

open access: yesJournal of Quaternary Science, EarlyView.
ABSTRACT The charring process can preserve archaeobotanical remains, providing valuable insights into past climates, agricultural practices, and plant growth conditions. However, the impact of charring on stable isotopes, especially at temperatures above 300°C, remains poorly understood.
Natálie Pernicová   +6 more
wiley   +1 more source

Elderberries as a potential supplement to improve vascular function in a SARS‐CoV‐2 environment

open access: yesJournal of Food Biochemistry, Volume 46, Issue 11, November 2022., 2022
Elderberry extract (EE) can target both viral infection and vascular dysfunction which could be a useful strategy to reduce morbidity and mortality relating to COVID‐19. Literature looks promising and builds a suggestion for investigating EE against COVID‐19. However, further in vitro and in vivo research is required to fully evaluate elderberries as a
Joseph Festa   +3 more
wiley   +1 more source

Myeloid‐derived suppressor cells and plasmacytoid dendritic cells are associated with oncogenesis of oral squamous cell carcinoma

open access: yesJournal of Oral Pathology &Medicine, Volume 52, Issue 1, Page 9-19, January 2023., 2023
Abstract Myeloid‐derived suppressor cells (MDSCs) help establish the tumor microenvironment by suppressing T‐cell response in tumor‐bearing hosts. Plasmacytoid dendritic cells (pDCs) activate antigen‐specific T cells, thereby, maximizing their antitumor effects.
Atsumu Kouketsu   +7 more
wiley   +1 more source

Catalase‐Encapsulated Nanoparticles via Surface Radical Polymerization for Periodontitis Therapy

open access: yesMacromolecular Materials and Engineering, EarlyView.
This study introduces catalase‐encapsulated nanoparticles (CAT NPs) designed to target the Nrf‐2/HO‐1 pathway for the treatment of periodontitis. CAT NPs demonstrate potent antioxidative and anti‐inflammatory properties, significantly reducing reactive oxygen species (ROS) and cytokine levels.
Tongtong Yan   +9 more
wiley   +1 more source

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