Results 211 to 220 of about 60,708 (241)
Serum Proteomic and Metabolomic Signatures of High Versus Low Physical Function in Octogenarians
Circulating factors are strongly implicated in modulating biological aging. In this study we show that the serum proteomic and metabolomic profile of high functioning octogenarians suggests lower activation of SASP, preservation of the tryptophan‐kynurenic pathway, higher lipophosphatidyl cholines promoting mitochondrial function, and reduced ...
Ceereena Ubaida‐Mohien+11 more
wiley +1 more source
Abstract Background Among erectile dysfunction (ED) caused by metabolic abnormalities, diabetes mellitus‐induced ED (DMED) progresses rapidly, manifests with severe symptoms, and shows reduced responsiveness to conventional medications. Hyperglycemia in the corpus cavernosum has been linked to the induction of both ferroptosis and oxidative stress ...
Sheng Xin+8 more
wiley +1 more source
Factors Affecting the Relationship Between Total and Unbound Bilirubin in Preterm and Term Infants
ABSTRACT Aim Newborn infants universally experience jaundice, most of which is physiologic, but in some high‐risk situations, it may lead to neurological dysfunction or death. Unbound bilirubin (Bf) may be the best predictor of bilirubin toxicity in this population. The goal of the study is to examine the relationship between total serum bilirubin (TSB)
Thomas Hegyi+6 more
wiley +1 more source
Mechanism of action of heme oxygenase. A study of heme degradation to bile pigment by 18O labeling.
John C. Docherty+3 more
openalex +1 more source
Understanding erythroid physiology and pathology in humanized mice: A closer look
Erythropoiesis, the formation of red blood cells (RBCs) from haematopoietic stem cells (HSCs), is vital for understanding conditions like anaemia and haemoglobinopathies. However, studying this process in vivo is challenging due to the lack of accurate models.
Lu Lu+7 more
wiley +1 more source