Results 211 to 220 of about 60,708 (241)

Serum Proteomic and Metabolomic Signatures of High Versus Low Physical Function in Octogenarians

open access: yesAging Cell, EarlyView.
Circulating factors are strongly implicated in modulating biological aging. In this study we show that the serum proteomic and metabolomic profile of high functioning octogenarians suggests lower activation of SASP, preservation of the tryptophan‐kynurenic pathway, higher lipophosphatidyl cholines promoting mitochondrial function, and reduced ...
Ceereena Ubaida‐Mohien   +11 more
wiley   +1 more source

Therapeutic potential of hesperidin in diabetes mellitus‐induced erectile dysfunction through Nrf2‐mediated ferroptosis and oxidative stress

open access: yesAndrology, EarlyView.
Abstract Background Among erectile dysfunction (ED) caused by metabolic abnormalities, diabetes mellitus‐induced ED (DMED) progresses rapidly, manifests with severe symptoms, and shows reduced responsiveness to conventional medications. Hyperglycemia in the corpus cavernosum has been linked to the induction of both ferroptosis and oxidative stress ...
Sheng Xin   +8 more
wiley   +1 more source

Nonessentiality of histidine 291 of Rhodospirillum rubrum ribulose-bisphosphate carboxylase/oxygenase as determined by site-directed mutagenesis.

open access: hybrid, 1986
Niyogi Sk   +7 more
openalex   +1 more source

Factors Affecting the Relationship Between Total and Unbound Bilirubin in Preterm and Term Infants

open access: yesActa Paediatrica, EarlyView.
ABSTRACT Aim Newborn infants universally experience jaundice, most of which is physiologic, but in some high‐risk situations, it may lead to neurological dysfunction or death. Unbound bilirubin (Bf) may be the best predictor of bilirubin toxicity in this population. The goal of the study is to examine the relationship between total serum bilirubin (TSB)
Thomas Hegyi   +6 more
wiley   +1 more source

Mechanism of action of heme oxygenase. A study of heme degradation to bile pigment by 18O labeling.

open access: hybrid, 1984
John C. Docherty   +3 more
openalex   +1 more source

Transcriptional control of the rat heme oxygenase gene by a nuclear protein that interacts with adenovirus 2 major late promoter

open access: hybrid, 1989
Maria Notomi Sato   +5 more
openalex   +1 more source

Understanding erythroid physiology and pathology in humanized mice: A closer look

open access: yesBritish Journal of Haematology, EarlyView.
Erythropoiesis, the formation of red blood cells (RBCs) from haematopoietic stem cells (HSCs), is vital for understanding conditions like anaemia and haemoglobinopathies. However, studying this process in vivo is challenging due to the lack of accurate models.
Lu Lu   +7 more
wiley   +1 more source

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