Results 71 to 80 of about 220,248 (385)

Gasotransmitters in Modern Medicine: Promises and Challenges in the Use of Porous Crystalline Carriers

Advanced Healthcare Materials, EarlyView.
This perspective provides an overview of the growing interest in utilizing various gasotransmitters—small gaseous signaling molecules namely nitric oxide (NO), carbon monoxide (CO), and hydrogen sulfide (H2S)—for several therapeutic applications, with emphasis on the potential use of porous materials as carriers to provide safe and controlled local ...
Rosana V. Pinto, Moisés L. Pinto, Christian Serre   +2 more
wiley   +1 more source

Impairment of neutrophil oxidative burst in children with sickle cell disease is associated with heme oxygenase-1

Haematologica, 2015
Sickle cell disease is a risk factor for invasive bacterial infections, and splenic dysfunction is believed to be the main underlying cause. We have previously shown that the liberation of heme in acute hemolysis can induce heme oxygenase-1 during ...
Ceri Evans, Katharine Orf, Erzsebet Horvath, Michael Levin, Josu De La Fuente, Subarna Chakravorty, Aubrey J. Cunnington   +6 more
doaj   +1 more source

Heme Oxygenase-1 in Kidney Health and Disease.

Antioxidants and Redox Signaling, 2016
SIGNIFICANCE Acute kidney injury (AKI) and chronic kidney disease (CKD) represent a considerable burden in healthcare. The heme oxygenase (HO) system plays an important role in regulating oxidative stress and is protective in a variety of human and ...
J. Lever, Ravindra Boddu, J. George, A. Agarwal   +3 more
semanticscholar   +1 more source

Antitumoral Efficacy of AuNRs‐Laden ECFCs In Vitro and In Vivo: Decoding the Heat and Rays Combo Treatment in Breast Cancer and Melanoma Cells

Advanced Healthcare Materials, EarlyView.
Endothelial Colony Forming Cells (ECFCs) acted as cellular cyborgs, stealthily transporting gold nanorods (AuNRs) into tumors to enable targeted near‐infrared (NIR) hyperthermia combined with radiotherapy. This approach triggers ferroptosis in melanoma and inhibits autophagy in breast cancer, revealing a tumor‐specific response to nanomaterial‐assisted
Cecilia Anceschi, Francesca Scavone, Paolo Armanetti, Luca Menichetti, Claudia Catarinicchia, Claudia Borri, Fulvio Ratto, Filippo Micheletti, Noemi Formica, Jessica Ruzzolini, Elena Frediani, Anastasia Chillà, Francesca Margheri, Mirko Severi, Rita Traversi, Patrizia Nardini, Daniele Guasti, Mario Del Rosso, Tommaso Del Rosso, Lisa Giovanelli, Cinzia Talamonti, Monica Mangoni, Isacco Desideri, Silvia Burchielli, Fabiola Pajar, Gabriella Fibbi, Anna Laurenzana   +26 more
wiley   +1 more source

Bilirubin Sensing Using Organic Electrochemical Transistors: Role of Gate Materials and Operational Parameters

Advanced Healthcare Materials, EarlyView.
This study explores PEDOT:PSS‐based OECTs as sensitive bilirubin sensors, revealing that polarizable gate electrodes (Au, Pt, glassy carbon) enable detection while non‐polarizable Ag/AgCl gates suppress response. Operational parameters modulate current direction, suggesting complex interfacial dynamics.
Yunjia Song, Sihui Xu, Onur Parlak
wiley   +1 more source

Nrf2, a Cap’n’Collar Transcription Factor, Regulates Induction of the Heme Oxygenase-1 Gene*

Journal of Biological Chemistry, 1999
Stress response elements, which mediate induction of the mouse heme oxygenase-1 (HO-1) gene by several agents, resemble the binding site for the activator protein-1 (Jun/Fos), Maf, and Cap’n’Collar/basic leucine zipper (CNC-bZIP) families of proteins. In
J. Alam, D. Stewart, Cheri L. Touchard, Sujji Boinapally, A. Choi, J. Cook   +5 more
semanticscholar   +1 more source

Carotinoid-Oxygenase in Chlorella

Zeitschrift für Naturforschung B, 1958
In Chlorella wurde ein bisher unbekanntes labiles Oxygenasesystem gefunden, das im Dunkeln mit großer Geschwindigkeit Sauerstoff auf Carotinoide überträgt und das durch Licht gehemmt wird. Vgl. dazu O. WARBURG, G. KRIPPAHL und W. SCHRÖDER, Wirkungsspektrum eines Photosynthese-Ferments, diese Z. 10 b, 631 [1955].
Otto Warburg, Wolfgang Völker, Hans-Siegfried Gewitz, Günter Krippahl   +3 more
openaire   +3 more sources

Understanding miR‐200c: an Important Player in Resistance to Cancer Treatment

Advanced Therapeutics, EarlyView.
How can one microRNA alter cancer's response to therapy? miR‐200c plays a central role in therapeutic resistance by modulating epithelial‐mesenchymal transition, apoptosis, cancer stemness features, and drug efflux. This review outlines the context‐dependent functions of miR‐200c in various cancers and highlights its potential as both a biomarker and a
Fatma Sanli, Omer Faruk Karatas
wiley   +1 more source

Immunohistochemical Expression of COX2 in Urothelial Carcinoma of the urinary bladder

Advanced Medical Journal
Background and objectives: Urothelial carcinoma of urinary bladder constitutes 90% of bladder cancer cases. Cyclo-oxygenase 2 as an immune-histochemical marker, is not expressed in normal tissues, while it is expressed in some cancers including ...
Shayan Khattab Omer, Jalal Ali Jalal, Zheen Othman   +2 more
doaj   +1 more source

A Lactobacillus rhamnosus strain induces a heme oxygenase dependent increase in Foxp3+ regulatory T cells. [PDF]

PLoS ONE, 2012
We investigated the consequences of feeding with a Lactobacillus species on the immune environment in GALT, and the role of dendritic cells and heme oxygenase-1 in mediating these responses.
Khalil Karimi, Nalaayini Kandiah, Jessie Chau, John Bienenstock, Paul Forsythe   +4 more
doaj   +1 more source