Results 81 to 90 of about 175,409 (339)
The effects of Bilirubin and Bilirubin-di-taurate on ischemia reperfusion injruy in a rat model of kidney transplantation [PDF]
, 2011 Background: Heme oxygenase-1 (HO-1) is the rate-limiting enzyme in the conversion of heme into biliverdin, carbon monoxide (CO) and free iron. Biliverdin is then subsequently reduced to bilirubin by the enzyme bilverdin reductase.
Thomas, Michael
core
Haem oxygenase: a reappraisal of the stoicheiometry
FEBS Letters, 1979 Haem oxygenase (EC 1.14.99.3) in rat liver microsomes was first described as a mixed function oxidase utilising cytochrome P-450 [I]. Immunochemical studies suggest that NADP(H)-cytochrome c reductase activity is an essential component of the enzyme [2]. Indeed, it has been suggested [3] following the use of partially purified enzyme preparations, that
Owen T.G. Jones +2 more
openaire +3 more sources
An Update: Enzymatic Synthesis for Industrial Applications
Angewandte Chemie International Edition, EarlyView.Biocatalysis has become a sustainable and cost‐competitive alternative to established chemical synthesis, enabling the enzyme‐based production of not only commodity chemicals but (non‐natural) amino acids, (rare) sugars, as well as synthetic nucleotides.
Thomas Bayer +4 more
wiley +1 more source
Iranian Journal of Allergy, Asthma and Immunology, 2013 Up-regulation of CD4+CD25+CD127low/- regulatory T cells (Tregs) is a new target in the treatment of asthma. Human bone marrow mesenchymal stem cells can up-regulate CD4+CD25+CD127low/- regulatory T cells in vitro, meanwhile, heme oxygenase-1 (HO-1 ...
Jian-guo Li +6 more
doaj
Phenolic metabolites of anthocyanins modulate mechanisms of endothelial function [PDF]
, 2015 Anthocyanins are reported to have vascular bioactivity, however their mechanisms of action are largely unknown. Evidence suggests that anthocyanins modulate endothelial function, potentially by increasing nitric oxide (NO) synthesis, or enhancing NO ...
Cassidy, Aedin +4 more
core +1 more source
Heme oxygenase 1 overexpression increases iron fluxes in Caco-2 cells
Biological Research, 2006 Heme oxygenase-1 is a microsomal enzyme that, when induced by stress, protects the cells from oxidative injury. Heme oxygenase-1 participates in the cleavage of the heme ring producing biliverdin, CO and ferrous Fe.
MARÍA JOSE MENDIBURO +3 more
doaj
Cytoprotective role of heme oxygenase-1 upregulation in progressive renal disease [PDF]
Einstein (São Paulo), 2009 Objective: This study evaluated the ability of heme oxygenase-1 to prevent or reverse renal fibrosis. Methods: Sprague-dawley male rats were submitted to unilateral ureteral obstruction and divided into groups: non-treated and hemin.
Matheus Corrêa Costa +9 more
doaj
Strontium Ranelate Elevates Expression of Heme Oxygenase-1 and Decreases Alveolar Bone Loss in Rats
eJournal of Oral Maxillofacial Research, 2018 Objectives: The purpose of this study was to determine the effects of strontium ranelate on ligature-induced periodontitis in rats and assess the putative involvement of heme oxygenase-1 (HO-1) pathway in these effects.
Ricardo Basto Souza +6 more
doaj +1 more source
Frontiers in Physiology, 2020 Carotenoids are almost universally distributed in living organisms. The oxidative metabolism by carotene oxygenase contributes to the metabolic processes of carotenoids.
Yue Jin +18 more
doaj +1 more source
Selective COX-2 inhibitors and risk of myocardial infarction [PDF]
, 2005 Selective inhibitors of cyclooxygenase- 2 ( COX- 2, ` coxibs') are highly effective anti-inflammatory and analgesic drugs that exert their action by preventing the formation of prostanoids.
Klauss, V. +3 more
core +1 more source