Results 91 to 100 of about 24,557 (298)

Phylogenetic and genomic analyses of the ribosomal oxygenases Riox1 (No66) and Riox2 (Mina53) provide new insights into their evolution

open access: yesBMC Evolutionary Biology, 2018
Background Translation of specific mRNAs can be highly regulated in different cells, tissues or under pathological conditions. Ribosome heterogeneity can originate from variable expression or post-translational modifications of ribosomal proteins.
Katharina E. Bräuer   +6 more
doaj   +1 more source

Systematic review and scoring‐based selection of pharmacokinetic models for precision dosing of vancomycin in neonates and children

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
This systematic review identified 112 population pharmacokinetic models of vancomycin in neonates and children. To support rational model selection for model‐informed precision, we developed and applied expert‐driven, transparent criteria that integrate both methodological rigour and clinical relevance.
Zoë Vander Elst   +8 more
wiley   +1 more source

Characterized cis-FeV(O)(OH) intermediate mimics enzymatic oxidations in the gas phase

open access: yesNature Communications, 2019
FeV(O)(OH) species have long been thought to play a role in a range of enzymatic oxidations, but their characterization has remained elusive. Here, using gas-phase ion spectroscopy, the authors characterize an FeV(O)(OH) species and find that its ...
Margarida Borrell   +4 more
doaj   +1 more source

Fatty acid oxygenase activity of human hair roots

open access: yesJournal of Lipid Research, 1993
The extent to which fatty acid oxygenases are activated in the normal epidermis is not known. Characterization of the regio- and stereospecificity of the monohydroxylated derivatives of arachidonic and linoleic acid produced by human hair roots is needed
AN Baer, FA Green
doaj   +1 more source

Catalysts on Demand: Selective Oxidations by Laboratory-Evolved Cytochrome P450 BM3 [PDF]

open access: yes, 2009
Efficient catalysts for selective oxidation of C-H bonds using atmospheric oxygen are highly desirable to decrease the economic and environmental costs associated with conventional oxidation processes.
Arnold, Frances H., Lewis, Jared C.
core   +2 more sources

Beyond CO2: Incorporating Bicarbonate, Dynamic Carbon Speciation, and Stoichiometric Plasticity Into Algal Growth Models

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT The design of biological carbon capture systems to uptake carbon dioxide by photoautotrophic cultivation of algae has been proposed to mitigate atmospheric carbon emissions. Multiple models to predict algal growth as a function of nutrients have been proposed, but few have delved into the complex dynamic reactions of algal growth as influenced
Elizabeth Flanagan   +2 more
wiley   +1 more source

Gasotransmitters: novel regulators of ion channels and transporters [PDF]

open access: yes, 2013
More than 25 years ago, it was a big surprise for physiologists that nitric oxide (NO) was identified as the endothelium derived relaxing factor which is responsible for endothelium-induced smooth muscle relaxation (Ignarro et al., 1987).
Mike Althaus, Wolfgang G. Clauss
core   +2 more sources

Thermodynamic Evaluation of Dual Substrate Growth

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Various C₁–C₂ compounds are increasingly available through electrochemical reduction of CO2. Although not always suitable as a sole substrate, these compounds can supplement a primary substrate like glucose to enhance microbial growth. Yet, the mechanisms underlying the effects of dual substrate consumption on growth rate and growth yield ...
Marit A. Verheijen   +3 more
wiley   +1 more source

The derivation of the formyl-group oxygen of chlorophyll b in higher plants from molecular oxygen. [PDF]

open access: yes, 1994
The mechanism of formation of the formyl group of chlorophyll b has long been obscure but, in this paper, the origin of the 7-formyl-group oxygen of chlorophyll b in higher plants was determined by greening etiolated maize leaves, excised from dark-grown
Abraham R. J.   +27 more
core   +1 more source

An Idea to Explore: From How to Why: Using Evolutionary Biochemistry to Inspire Biochemistry Education

open access: yesBiochemistry and Molecular Biology Education, EarlyView.
ABSTRACT Traditional biochemistry instruction often emphasizes mechanistic detail, that is, how molecules and pathways function, without equally addressing why they have their present forms. This fact‐centered approach can leave students overwhelmed and disconnected from the broader scientific narrative.
Alberto Vázquez‐Salazar
wiley   +1 more source

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