Results 121 to 130 of about 13,374 (242)

Calebin A mitigates oxidative stress and inflammation in diabetic nephropathy via Nrf2/HO‐1 and NF‐κB signaling pathways

Journal of Diabetes Investigation, EarlyView.
Representative histological images of kidney tissues stained with hematoxylin and eosin (H&E) at 400× magnification (n = 6). ABSTRACT Background Diabetic nephropathy (DN) is a common and serious microvascular complication of diabetes mellitus, primarily driven by persistent hyperglycemia‐induced oxidative stress and chronic inflammation.
Reyhane Ghayour Vatanparast, Mahdieh Aliyari, Mahla Palizkaran Yazdi, Soodeh Alidadi, Mohammad Reza Sokhanvar, Sercan Karav, Prashant Kesharwani, Hossein Hosseini, Amirhossein Sahebkar   +8 more
wiley   +1 more source

Profiling Inhibitor Scaffolds for the Cancer Target Jumonji-C Domain-Containing Protein 6. [PDF]

ChemMedChem
Corner TP, Salah E, Tumber A, Holt-Martyn JP, Brewitz L, Schofield CJ.   +5 more
europepmc   +1 more source

OsCPN10a, cooperating with OsCPN20 and OsHSP60‐3B negatively regulate ABA signaling and enhance seed storability in rice

Journal of Integrative Plant Biology, EarlyView.
Abscisic acid signaling homeostasis is essential for seed storability. The molecular chaperone OsCPN10a enhances rice seed storability by forming a trimeric chaperone complex with OsCPN20‐OsHSP60‐3B that attenuates abscisic acid signaling via direct interaction with OsPYL10‐OsABIL1, thereby maintaining starch integrity and offering a promising target ...
Sufeng Liao, Yidong Wei, Yongsheng Zhu, Kunyang Li, Ting Chen, Shuai Zhao, Fangxi Wu, Jinlan Wang, Pengbo Yu, Hongguang Xie, Liping Chen, Qiuhua Cai, Huaan Xie, Jianfu Zhang   +13 more
wiley   +1 more source

Structural and functional consequences of aspartate/asparagine-β-hydroxylase variants causing Traboulsi syndrome. [PDF]

J Biol Chem
Hou CX, Brasnett A, Rabe P, Schofield CJ, Brewitz L.   +4 more
europepmc   +1 more source

Convergence and parallelism in the evolution of plant metabolism

Journal of Integrative Plant Biology, EarlyView.
Similar traits in different organisms may originate from shared ancestry or evolve independently. The terminology used to define phenotypic similarity is often confusing. This review attempts to clarify the definitions and present examples from plant domestication and specialized metabolism to explain how complex traits evolve repeatedly in plants ...
Federico Scossa, Mustafa Bulut, Thomas Naake, John C. D'Auria, Alisdair R. Fernie   +4 more
wiley   +1 more source

Study and Modification of the Polycyclic Aromatic Hydrocarbon Degradation Gene Cluster in <i>Burkholderia</i> sp. FM-2. [PDF]

Microorganisms
Ma J, Zhai Y, Cui Y, Gao G, Ying M, Zhao Y, Antunes A, Huang L, Li M.   +8 more
europepmc   +1 more source

Plastid genome structure and phylogenomics of the freshwater red algal order Batrachospermales (Rhodophyta)

Journal of Phycology, EarlyView.
Abstract For the freshwater red algal order Batrachospermales, the number of plastid genomes available is relatively small compared to the number of genera. Fully assembled plastid genomes can provide insights into plastid evolution and crucial data for phylogenetic reconstruction.
Roseanna M. Crowell, Nadia M. Lemes Da Silva, Monica O. Paiano, Morgan L. Vis, Orlando Necchi Jr.   +4 more
wiley   +1 more source

Evidence human FTO catalyses hydroxylation of N6-methyladenosine without direct formation of a demethylated product contrasting with ALKBH5/2/3 and bacterial AlkB. [PDF]

Nucleic Acids Res
Kaur S, Maheswaran P, Kaur S, Lai Y, Salah E, Zhang D, Shishodia S, Schofield CJ, Aik WS.   +8 more
europepmc   +1 more source

Temporal stability and spatial patterns of genetic diversity in populations of the climate‐vulnerable fucoid Scytothalia dorycarpa

Journal of Phycology, EarlyView.
Abstract Climate change is driving the loss of genetic diversity, potentially limiting species' capacity to adapt to environmental change. Detecting changes in genetic diversity requires replicated temporal data, which is lacking for most species. Here, we combined contemporary and historical specimens of the climate‐vulnerable fucoid Scytothalia ...
Jane M. Edgeloe, Melinda A. Coleman, Georgina V. Wood, Samuel Starko, Matt J. Nimbs, Jacqueline Batley, Thomas Wernberg   +6 more
wiley   +1 more source

Rieske Oxygenases: Powerful Models for Understanding Nature's Orchestration of Electron Transfer and Oxidative Chemistry. [PDF]

Biochemistry
Miao H, Schmidt S.
europepmc   +1 more source