Results 191 to 200 of about 13,613 (257)

Systematic review and scoring‐based selection of pharmacokinetic models for precision dosing of vancomycin in neonates and children

British Journal of Clinical Pharmacology, Volume 92, Issue 7, Page 2028-2048, July 2026.
This systematic review identified 112 population pharmacokinetic models of vancomycin in neonates and children. To support rational model selection for model‐informed precision, we developed and applied expert‐driven, transparent criteria that integrate both methodological rigour and clinical relevance.
Zoë Vander Elst, Pieter‐Jan Spiessens, Dorian Vanneste, Nada Dia, Matthias Gijsen, Isabel Spriet, Karel Allegaert, Erwin Dreesen, Anne Smits   +8 more
wiley   +1 more source

Combining biocatalytic and radical retrosynthesis for efficient chemoenzymatic synthesis of natural products.

Chem Soc Rev
Renata H.
europepmc   +1 more source

Thermodynamic Evaluation of Dual Substrate Growth

Biotechnology and Bioengineering, Volume 123, Issue 7, Page 1825-1835, July 2026.
ABSTRACT Various C₁–C₂ compounds are increasingly available through electrochemical reduction of CO2. Although not always suitable as a sole substrate, these compounds can supplement a primary substrate like glucose to enhance microbial growth. Yet, the mechanisms underlying the effects of dual substrate consumption on growth rate and growth yield ...
Marit A. Verheijen, Tim Meyboom, Mark C. M. van Loosdrecht, Rebeca Gonzalez‐Cabaleiro   +3 more
wiley   +1 more source

Unlocking microbial potential: advances in omics and bioinformatics for aromatic hydrocarbon degradation. [PDF]

World J Microbiol Biotechnol
Vidal-Silva IM, Loza A, Gutierrez-Rios RM.   +2 more
europepmc   +1 more source

Identification of PRKCB, NLRC4, and TNFSF10 as Key Regulators of the Lipid Metabolism‐Autophagy Network in Atherosclerosis

Cell Biochemistry and Function, Volume 44, Issue 7, July 2026.
ABSTRACT Background The occurrence and development of atherosclerosis (AS) are closely related to disorders of lipid metabolism and dysfunction of autophagy. However, the key regulatory genes and immune microenvironment characteristics require further exploration. Methods This study integrated the bulk transcriptome and single‐cell RNA sequencing data,
Min Li, Yanjun Sun, Yanyi Sun, Zhenyue Chen   +3 more
wiley   +1 more source

Draft genome sequence of the meloxicam-degrading <i>Gordonia alkanivorans</i> IEGM 1277 strain. [PDF]

Microbiol Resour Announc
Tyan SM, Ivshina IB.
europepmc   +1 more source

α7nAChR agonist GTS‐21 ameliorates sepsis‐induced acute kidney injury via MEF2/PGC‐1α/HO‐1 axis in mice

Clinical and Translational Medicine, Volume 16, Issue 7, July 2026.
This diagram illustrates opposing pathways regulating AKI (acute kidney injury). The left pathway shows LPS/TLR4 triggering mitochondrial damage (low MMP, Cyt C release, ROS) leading to apoptosis. The right pathway shows α7nAChR agonists activating MEF2 to upregulate PGC‐1α/HO‐1, promoting mitochondrial biogenesis and inhibiting injury, highlighting ...
Yu‐Jia Tang, Hui‐Ying Liu, Na‐Qi Li, Xin Zhang, Yi‐Lu Lin, Yan Zhang, Yao Li, Jia‐Le Deng, Pei‐Lin Yang, Qing‐Min Meng, Yi‐Jin Tang, Zi‐Yue Zhang, Si‐Han Guan, Kai Kang, Hong‐Liang Wang, Yang Gao   +15 more
wiley   +1 more source

Mechanistic Insights into Dioxygen Transport Routes in the PHD2 Oxygenase from Long-Time Scale Simulations. [PDF]

Biochemistry
Wiley B, Furini S, Domene C.
europepmc   +1 more source

Therapeutic Potential of Berberis vulgaris in Modulating Metabolic Syndrome Biomarkers: Mechanistic Insights and Functional Food Implications

Food Frontiers, Volume 7, Issue 4, July 2026.
ABSTRACT Barberry (Berberis vulgaris) has emerged as a promising functional food candidate for the management of metabolic syndrome due to its diverse bioactive constituents, particularly berberine. This review synthesizes current experimental and clinical evidence regarding its effects on glycemic control, lipid metabolism, blood pressure regulation ...
Fakhar Shahid, Ifrah Jabeen, Muhammad Inam‐ur‐Raheem, Amin Mousavi Khaneghah, Muhammad Abid, Rana Muhammad Aadil   +5 more
wiley   +1 more source

Unspecific Peroxygenases-Catalyzed Oxidation of Pharmaceutical Compounds Considered Emerging Contaminants. [PDF]

Chembiochem
Torres-Aguirre A, López-López A, Avelar M, Alcalde M, Ayala M.   +4 more
europepmc   +1 more source