Results 331 to 340 of about 82,259 (373)
Some of the next articles are maybe not open access.
Antioxidants & Redox Signaling, 2004
The importance of heme oxygenases in heme catabolism, iron utilization, and cellular signaling has been recognized for many years and is a well studied process in eukaryotes. Through the accessibility of an increasing number of bacterial genomes, it has become evident that heme oxygenases are also widespread in prokaryotes. In these organisms, the heme
openaire +2 more sources
The importance of heme oxygenases in heme catabolism, iron utilization, and cellular signaling has been recognized for many years and is a well studied process in eukaryotes. Through the accessibility of an increasing number of bacterial genomes, it has become evident that heme oxygenases are also widespread in prokaryotes. In these organisms, the heme
openaire +2 more sources
Oxygenases, Thwarted Oxygenases, and Oxygen-dependent Halogenases
2022Oxygenases, both flavin-dependent and iron-dependent, act on all classes of natural products, often late in scaffold maturation, to introduce oxygen functional groups, including hydroxyl and epoxide groups. The hydroxyl groups then function as nucleophiles for alkylations, acylations, and glycosylations.
openaire +1 more source
Cofactorless oxygenases guide anthraquinone-fused enediyne biosynthesis
Nature Chemical Biology, 2023Chun Gui +7 more
semanticscholar +1 more source
Current Opinion in Chemical Biology, 2002
Our understanding of the biological significance and chemical properties of non-heme iron oxygenases has increased dramatically in recent years. New group members have emerged from genome sequences and biochemical analyses. Spectroscopic and crystallographic studies have provided critical insights into catalysis.
Matthew J, Ryle, Robert P, Hausinger
openaire +2 more sources
Our understanding of the biological significance and chemical properties of non-heme iron oxygenases has increased dramatically in recent years. New group members have emerged from genome sequences and biochemical analyses. Spectroscopic and crystallographic studies have provided critical insights into catalysis.
Matthew J, Ryle, Robert P, Hausinger
openaire +2 more sources
Oxidative biotransformations using oxygenases
Current Opinion in Chemical Biology, 2002Considerable progress has been made in manipulating oxidative biotransformations using oxygenases. Substrate acceptance, catalytic activity, regioselectivity and stereoselectivity have been improved significantly by substrate engineering, enzyme engineering or biocatalyst screening.
Zhi, Li +6 more
openaire +2 more sources
Heme oxygenase-1 and heme oxygenase-2 expression in bruises
Forensic Science, Medicine, and Pathology, 2015The first step in catabolism of hemoglobin in a bruise is performed by the enzyme heme oxygenase, which produces biliverdin that is then reduced to bilirubin. The development of yellow coloration in bruises can be attributed to local accumulation of degradation products of hemoglobin, including bilirubin, but it is not clear why there is a delay before
Neil E I, Langlois +3 more
openaire +2 more sources
2000
Abstract Haem oxygenase (HO) is an amphipathic microsomal protein which catalyses the regiospecific oxidative degradation of haem to biliverdin, CO, and Fe in the presence of NADPH-cytochrome P-450 reductase as an electron donor (1-4). Haem degradation is physiologically important because it is the process not only of dissimilation of ...
openaire +1 more source
Abstract Haem oxygenase (HO) is an amphipathic microsomal protein which catalyses the regiospecific oxidative degradation of haem to biliverdin, CO, and Fe in the presence of NADPH-cytochrome P-450 reductase as an electron donor (1-4). Haem degradation is physiologically important because it is the process not only of dissimilation of ...
openaire +1 more source