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Journal of Microbiology, Immunology and Infection, 2021 Increased heme levels, anemia, and desaturation occur during infection. We aimed to compare the levels of heme, heme oxygenase-1 (HO-1), ferritin, and bilirubin in coronavirus disease 2019 (COVID-19) patients at different saturation levels. Heme and HO-1
Wen-Lin Su +2 more
exaly +3 more sources
Alternative 5' untranslated regions are involved in expression regulation of human heme oxygenase-1. [PDF]
PLoS ONE, 2013 The single nucleotide polymorphism rs2071746 and a (GT)n microsatellite within the human gene encoding heme oxygenase-1 (HMOX1) are associated with incidence or outcome in a variety of diseases.
Marcel Kramer +8 more
doaj +1 more source
Heme, Heme Oxygenase-1, Statins, and SARS-CoV-2
Antioxidants, 2023 Heme, a metalloporphyrin, or more specifically, a tetrapyrrole containing ferrous iron, is an ancient molecule [...]
David K. Stevenson +2 more
doaj +1 more source
Endoplasmic reticulum anchored heme-oxygenase 1 faces the cytosol
Haematologica, 2012 Heme-oxygenase 1 is an endoplasmic reticulum-anchored enzyme that breaks down heme into iron, carbon monoxide and biliverdin. Heme is a hydrophobic co-factor in many proteins, including hemoglobin.
Yehonatan Gottlieb +4 more
doaj +1 more source
Frontiers in Cellular Neuroscience, 2020 Subarachnoid hemorrhage is a specific, life-threatening form of hemorrhagic stroke linked to high morbidity and mortality. It has been found that the choroid plexus of the brain ventricles forming the blood-cerebrospinal fluid barrier plays an important ...
Peter Solár +10 more
doaj +1 more source
Pharmacological Significance of Heme Oxygenase 1 in Prostate Cancer
Current Issues in Molecular Biology, 2023 Heme oxygenase 1 (HO-1) is a detoxifying antioxidant microsomal enzyme that regulates inflammation, apoptosis, cell proliferation, and angiogenesis in prostate cancer (PCa).
Mohamed Ben-Eltriki +3 more
doaj +1 more source
How Heme Oxygenase-1 Prevents Heme-Induced Cell Death. [PDF]
PLoS ONE, 2015 Earlier observations indicate that free heme is selectively toxic to cells lacking heme oxygenase-1 (HO-1) but how this enzyme prevents heme toxicity remains unexplained.
Lilibeth Lanceta +3 more
doaj +1 more source
Clinical Significance of Heme Oxygenase 1 in Tumor Progression
Antioxidants, 2021 Heme oxygenase 1 (HO-1) plays a key role in cell adaptation to stressors through the antioxidant, antiapoptotic, and anti-inflammatory properties of its metabolic products.
Mariapaola Nitti +3 more
doaj +1 more source
Gynecology Obstetrics & Reproductive Medicine, 2022 OBJECTIVE: To examine early pregnancy levels of serum heme oxygenase-1, soluble vascular endothelial growth factor receptor-1, B-cell lymphoma/leukemia-2 in relation to unfavorable pregnancy outcomes, including preeclampsia, fetal growth restriction ...
Havva Sutcu +4 more
doaj +1 more source
Heme Oxygenase1 Level in Normotensive Pregnancy and Preeclampsia with Severe Features
Indonesian Journal of Obstetrics and Gynecology, 2016 Objective: To understand the relationship of heme oxygenase-1 (HO-1) level between normotensive pregnancy and preeclampsia with severe features. Method: The cross sectional study was conducted in the Department of Obstetrics and Gynecology, Faculty
Christian Homenta +2 more
doaj +1 more source