Results 141 to 150 of about 10,829 (193)
Serendipity, steroids and science. [PDF]
J Steroid Biochem Mol BiolSharifi N.
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AlphaFold-driven discovery of oxysterol-binding protein-related protein-phosphoinositide 3-, 4-, and 5-phosphatase interactions using new generation confidence scores. [PDF]
Protein SciDall'Armellina F, Urbé S, Rigden DJ.
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Androgen metabolism in prostate cancer: recent advances.
EndocrinologySharifi N.
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Autism-associated oxysterol regulates GABAergic neurogenesis and subtype fates
Cruz-Santos M +7 more
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Oxysterols in Infectious Diseases
2023Oxysterols have emerged as important bioactive lipids in the immune response to infectious diseases. This chapter discusses our current knowledge of oxysterols and their receptors in bacterial and viral infections of the respiratory and gastrointestinal tracts.
Foo, Cheng X. +2 more
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Oxysterols and oxysterol binding proteins: role in lipid metabolism and atherosclerosis
Annals of Medicine, 2004 Oxidized derivatives of cholesterol have been investigated actively for decades in the context of the oxidative hypothesis of atherosclerosis. Oxysterols arise in our tissues as a result of enzymatic or non-enzymatic oxidation reactions and are also obtained from dietary sources.
Vesa M Olkkonen, Markku Lehto
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Oxysterols and atherosclerosis
Atherosclerosis, 1999Oxysterols are present in human atherosclerotic plaque and are suggested to play an active role in plaque development. Moreover, the oxysterol:cholesterol ratio in plaque is much higher than in normal tissues or plasma. Oxysterols in plaque are derived both non-enzymically, either from the diet and/or from in vivo oxidation, or (e.g.
A J, Brown, W, Jessup
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Oxysterols and Alzheimer's disease
Acta Neurologica Scandinavica, 2006There is a clear link between cholesterol turnover and neurodegenerative diseases and hypercholesterolemia is an established risk factor for Alzheimer's disease (AD). The failure to demonstrate a transfer of cholesterol from the circulation into the brain in humans and experimental animals makes it difficult to explain the link between ...
Björkhem, I +4 more
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2018
Oxysterols are oxygenated derivatives of cholesterol formed in the human body or ingested in the diet. By modulating the activity of many proteins (for instance, liver X receptors, oxysterol-binding proteins, some ATP-binding cassette transporters), oxysterols can affect many cellular functions and influence various physiological processes (e.g ...
Fabien, Riols, Justine, Bertrand-Michel
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Oxysterols are oxygenated derivatives of cholesterol formed in the human body or ingested in the diet. By modulating the activity of many proteins (for instance, liver X receptors, oxysterol-binding proteins, some ATP-binding cassette transporters), oxysterols can affect many cellular functions and influence various physiological processes (e.g ...
Fabien, Riols, Justine, Bertrand-Michel
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Future Cardiology, 2009
Oxysterols are biologically active molecules that result from the oxidation of cholesterol. Several oxysterols are found in macrophages and macrophage-derived 'foam cells' in atherosclerotic tissue. Lipophilic oxysterols penetrate cell membranes and, therefore, their concentrations can reach harmful levels in endothelial and smooth muscle cells located
Valeriy, Lukyanenko +1 more
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Oxysterols are biologically active molecules that result from the oxidation of cholesterol. Several oxysterols are found in macrophages and macrophage-derived 'foam cells' in atherosclerotic tissue. Lipophilic oxysterols penetrate cell membranes and, therefore, their concentrations can reach harmful levels in endothelial and smooth muscle cells located
Valeriy, Lukyanenko +1 more
openaire +2 more sources