Results 1 to 10 of about 13,956 (157)
Impact of Oxysterols on Cell Death, Proliferation, and Differentiation Induction: Current Status
Cells, 2021 Oxysterols are oxidized derivatives of cholesterol produced by enzymatic activity or non-enzymatic pathways (auto-oxidation). The oxidation processes lead to the synthesis of about 60 different oxysterols.
Fábio Alessandro de Freitas +2 more
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Effects of Oxysterols on Immune Cells and Related Diseases
Cells, 2022 Oxysterols are the products of cholesterol oxidation. They have a wide range of effects on several cells, organs, and systems in the body. Oxysterols also have an influence on the physiology of the immune system, from immune cell maturation and migration
Fábio Alessandro de Freitas +2 more
exaly +3 more sources
Oxysterols in the Immune Response to Bacterial and Viral Infections
Cells, 2022 Oxidized cholesterols, the so-called oxysterols, are widely known to regulate cholesterol homeostasis. However, more recently oxysterols have emerged as important lipid mediators in the response to both bacterial and viral infections.
Cheng Xiang Foo +2 more
exaly +3 more sources
Redox Biology, 2021 Among Alzheimer's disease (AD) brain hallmarks, the presence of reactive astrocytes was demonstrated to correlate with neuronal loss and cognitive deficits.
Erica Staurenghi +2 more
exaly +3 more sources
Journal of Lipid Research, 1998 Early fatty streaks and advanced lesions are characterized by the deposition of cholesterol and cholesterol oxidation products (oxysterols). Oxysterols have been shown to be cytotoxic and pro-atherogenic compared to cholesterol and are found in ...
D.F. Vine +4 more
exaly +3 more sources
Oxysterols: From redox bench to industry
Redox Biology, 2022 More and more attention is nowadays given to the possible translational application of a great number of biochemical and biological findings with the involved molecules.
Giuseppe POLI +2 more
exaly +3 more sources
HSD3B1 is an oxysterol 3β-hydroxysteroid dehydrogenase in human placenta
Open Biology, 2023 Most biologically active oxysterols have a 3β-hydroxy-5-ene function in the ring system with an additional site of oxidation at C-7 or on the side-chain.
Alison Dickson +6 more
doaj +1 more source
BMC Medicine, 2023 Background Breast cancer is the most commonly diagnosed cancer in women worldwide, and underlying mechanistic pathways associated with breast cancer-specific and non-breast cancer-related deaths are of importance.
Nina Sophia Decker +8 more
doaj +1 more source
Endothelial cells, endoplasmic reticulum stress and oxysterols [PDF]
, 2017 Oxysterols are bioactive lipids that act as regulators of lipid metabolism, inflammation, cell viability and are involved in several diseases, including atherosclerosis.
Canonico, B. +10 more
core +6 more sources
Localization of sterols and oxysterols in mouse brain reveals distinct spatial cholesterol metabolism [PDF]
, 2020 Dysregulated cholesterol metabolism is implicated in a number of neurological disorders. Many sterols, including cholesterol and its precursors and metabolites, are biologically active and important for proper brain function. However, spatial cholesterol
Angelini, Roberto +10 more
core +2 more sources