Results 21 to 30 of about 9,669 (153)

Evaluating the oxysterol combination of 22(S)-hydroxycholesterol and 20(S)-hydroxycholesterol in periodontal regeneration using periodontal ligament stem cells and alveolar bone healing models

open access: yesStem Cell Research & Therapy, 2017
Background Oxysterols, oxygenated by-products of cholesterol biosynthesis, play roles in various physiological and pathological systems. However, the effects of oxysterols on periodontal regeneration are unknown.
Jin-Sun Lee   +4 more
doaj   +1 more source

Oxysterols present in Alzheimer's disease brain induce synaptotoxicity by activating astrocytes: A major role for lipocalin-2

open access: yesRedox Biology, 2021
Among Alzheimer's disease (AD) brain hallmarks, the presence of reactive astrocytes was demonstrated to correlate with neuronal loss and cognitive deficits.
Erica Staurenghi   +10 more
doaj   +1 more source

Inhibition of herpes simplex-1 virus replication by 25-hydroxycholesterol and 27-hydroxycholesterol

open access: yesRedox Biology, 2017
Oxysterols are known pleiotropic molecules whose antiviral action has been recently discovered. Here reported is the activity of a panel of oxysterols against HSV-1 with the identification of a new mechanism of action.
Valeria Cagno   +9 more
doaj   +1 more source

Oxysterols Protect Epithelial Cells Against Pore-Forming Toxins

open access: yesFrontiers in Immunology, 2022
Many species of bacteria produce toxins such as cholesterol-dependent cytolysins that form pores in cell membranes. Membrane pores facilitate infection by releasing nutrients, delivering virulence factors, and causing lytic cell damage - cytolysis ...
Thomas J. R. Ormsby   +6 more
doaj   +1 more source

Circulating Oxysterols in Alzheimer’s disease: A Systematic Review and Meta-analysis [PDF]

open access: yes, 2022
Despite decades of research, the cause and series of events underlying the advancement of Alzheimer’s disease (AD) has not yet been established. Lipids and especially cholesterol levels have been proposed to be implicated in AD. Several studies have been
Ademowo, OS.   +5 more
core   +1 more source

Simvastatin reduces circulating oxysterol levels in men with hypercholesterolaemia

open access: yesRedox Biology, 2018
Oxysterols (OHC) are biologically active cholesterol metabolites circulating in plasma that may be formed enzymatically (e.g. 24S-OHC, 25-OHC and 27-OHC) or by autoxidative mechanisms (e.g. 7-ketocholesterol, 7β-OHC and 25-OHC).
Irundika H.K. Dias   +5 more
doaj   +1 more source

Sterols and oxysterols [PDF]

open access: yes, 2009
The ingredients of animal feed formulation, especially the fatty sources, play a significant role in the production of high-quality food of animal origin. Industrial fat by-products are a major source of feeding fats in Europe. The main objectives of the
Ubhayasekera, S. J. Kumari A.
core   +1 more source

Oxysterols

open access: yes, 2002
Oxysterols are oxygenated derivatives of cholesterol that are intermediates or even end products in cholesterol excretion pathways. Because of their ability to pass cell membranes and the blood-brain barrier at a faster rate than cholesterol itself, they
Ingemar Björkhem   +3 more
core   +1 more source

Oxysterols: A world to explore [PDF]

open access: yes, 2010
Oxysterols (oxidized derivatives of cholesterol and phytosterols) can be generated in the human organism through different oxidation processes, some requiring enzymes.
Menendez-Carreño, M. (María)   +7 more
core   +1 more source

Oxysterols in Autoimmunity

open access: yes, 2019
Cholesterol is a member of the sterol family that plays essential roles in biological processes, including cell membrane stability and myelin formation. Cholesterol can be metabolized into several molecules including bile acids, hormones, and oxysterols.
Caroline Pot   +5 more
core   +1 more source

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