Synthetic Vasopressin and Oxytocin Analogs and Their Potential Use in Hemorrhagic, Traumatic and Septic Shock: A Personal Perspective [PDF]
As one of us has stated many years ago, “shock is a significant and sustained loss of effective circulating blood volume. It will eventuate in hypoperfusion of critical peripheral tissues, thus leading to a deficit in transcapillary exchange function in ...
Altura BM +3 more
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Oxytocin and Estrogen Receptor β in the Brain: An Overview
Oxytocin is a neuropeptide synthesized primarily by neurons of the paraventricular and supraoptic nuclei of the hypothalamus. These neurons have axons that project into the posterior pituitary and release oxytocin into the bloodstream to promote labor ...
Alexandra eAcevedo-Rodriguez +2 more
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Increased Serum and Urinary Oxytocin Concentrations after Nasal Administration in Beagle Dogs
In recent years more and more studies have revealed the effect of extraneous oxytocin on the social behavior of dogs. The distribution of administered oxytocin in different physiologically relevant compartments is important because this knowledge forms ...
Andrea Temesi +4 more
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Objective: Induction of labor (IOL), using intravenous oxytocin, is the artificial initiation of labor before its spontaneous onset for the purpose of delivery of the fetoplacental unit.
Seema Chopra +3 more
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Oxytocin is implicated in social memory deficits induced by early sensory deprivation in mice [PDF]
Acknowledgements We thank Miss Jia-Yin and Miss Yu-Ling Sun for their help in breading the mice. Funding This work was supported by grants from the National Natural Science Foundation of China (81200933 to N.-N. Song; 81200692 to L.
Chen, Ling +11 more
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Oxytocin, a hypothalamic neuropeptide essential for breastfeeding, is mainly produced in oxytocin neurons in the supraoptic nucleus (SON) and paraventricular nucleus.
Dongyang Li +8 more
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Systemic effects of oxytocin on male sexual activity via the spinal ejaculation generator in rats
Oxytocin is produced in the hypothalamus and stimulates uterine contraction and milk ejection. While many people consider oxytocin to be a female hormone, it is reported that, in men, the plasma oxytocin level increases markedly after ejaculation ...
Takumi Oti +2 more
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Association between oxytocin receptor gene polymorphisms and self-rated 'empathic concern' in schizophrenia [PDF]
The nonapeptide oxytocin (OXT) and its receptor (OXTR) have been implicated in social cognition, empathy, emotion and stress regulation in humans. Previous studies reported associations between OXT and OXTR genetic polymorphisms and risk for disorders ...
Brockmann, Eva-Maria +5 more
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Central mechanisms mediating the hypophagic effects of oleoylethanolamide and N-acylphosphatidylethanolamines: different lipid signals? [PDF]
The spread of "obesity epidemic" and the poor efficacy of many anti-obesity therapies in the long-term highlight the need to develop novel efficacious therapy. This necessity stimulates a large research effort to find novel mechanisms controlling feeding
Gaetani, Silvana +4 more
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From autism to eating disorders and more: the role of oxytocin in neuropsychiatric disorders [PDF]
Oxytocin (oxy) is a pituitary neuropeptide hormone synthesized from the paraventricular and supraoptic nuclei within the hypothalamus. Like other neuropeptides, oxy can modulate a wide range of neurotransmitter and neuromodulator activities. Additionally,
Di Bonaventura, Maria Vittoria Micioni +3 more
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