Oxytocin exerts harmful cardiac repolarization prolonging effects in drug-induced LQTS [PDF]
Background: Oxytocin is used therapeutically in psychiatric patients. Many of these also receive anti-depressant or anti-psychotic drugs causing acquired long-QT-syndrome (LQTS) by blocking HERG/IKr.
Bode Christoph+12 more
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The involvement of actin, calcium channels and exocytosis proteins in somato-dendritic oxytocin and vasopressin release [PDF]
Hypothalamic magnocellular neurons release vasopressin and oxytocin not only from their axon terminals into the blood, but also from their somata and dendrites into the extracellular space of the brain, and this can be regulated independently ...
Leng, Gareth, Ludwig, Mike, Tobin, Vicky
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Oxytocin at physiological concentrations evokes adrenocorticotropin (ACTH) release from corticotrophs by increasing intracellular free calcium mobilized mainly from intracellular stores. Oxytocin displays synergistic or additive effects on ACTH-releasing factor or arginine vasopressin-induced ACTH secretion, respectively [PDF]
The potency of oxytocin (OT) in evoking ACTH secretion by isolated, superfused rat adenohypophyseal corticotrophs and its enhancement by CRF and arginine vasopressin (AVP) were analyzed.
Dayanithi, G.+3 more
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Anxious to see you: Neuroendocrine mechanisms of social vigilance and anxiety during adolescence. [PDF]
Social vigilance is a behavioral strategy commonly used in adverse or changing social environments. In animals, a combination of avoidance and vigilance allows an individual to evade potentially dangerous confrontations while monitoring the social ...
Cassano G. B.+6 more
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Prevention of postpartum hemorrhage in low-resource settings: current perspectives. [PDF]
BackgroundPostpartum hemorrhage (PPH) is the leading cause of maternal death in low-income countries and is the primary cause of approximately one-quarter of global maternal deaths.
Bell, Suzanne+2 more
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Embodied Precision : Intranasal Oxytocin Modulates Multisensory Integration [PDF]
© 2018 Massachusetts Institute of Technology.Multisensory integration processes are fundamental to our sense of self as embodied beings. Bodily illusions, such as the rubber hand illusion (RHI) and the size-weight illusion (SWI), allow us to investigate ...
Aikaterini Fotopoulou+6 more
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Neuroenhancement of exposure therapy in anxiety disorders [PDF]
Although exposure-based treatments and anxiolytic medications are more effective than placebo for treating anxiety disorders, there is still considerable room for further improvement.
Curtiss, Joshua+2 more
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Toward molecular neuroeconomics of obesity [PDF]
Because obesity is a risk factor for many serious illnesses such as diabetes, better understandings of obesity and eating disorders have been attracting attention in neurobiology, psychiatry, and neuroeconomics. This paper presents future study directions by unifying (i) economic theory of addiction and obesity (Becker and Murphy, 1988; Levy 2002 ...
arxiv
Epigenetic modification of the oxytocin receptor gene is associated with emotion processing in the infant brain [PDF]
The neural capacity to discriminate between emotions emerges early in development, though little is known about specific factors that contribute to variability in this vital skill during infancy.
Connelly, J.+4 more
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Oxytocin makes us trusting but not gullible [PDF]
Originally known for its role in childbirth and lactation, oxytocin (OT) has recently proved to play a key role in social behavior. Deprived of OT, humans are unable to recognize and to bond to their peers.
Anthony Lane+4 more
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