Results 61 to 70 of about 182,621 (379)

Oxytocin exerts harmful cardiac repolarization prolonging effects in drug-induced LQTS

International Journal of Cardiology: Heart & Vasculature, 2022
Background: Oxytocin is used therapeutically in psychiatric patients. Many of these also receive anti-depressant or anti-psychotic drugs causing acquired long-QT-syndrome (LQTS) by blocking HERG/IKr.
Paul Kreifels, Ilona Bodi, Tibor Hornyik, Gerlind Franke, Stefanie Perez-Feliz, R. Lewetag, Robin Moss, Alessandro Castiglione, David Ziupa, Manfred Zehender, Michael Brunner, Christoph Bode, Katja E. Odening   +12 more
doaj  

Effects of route of administration on oxytocin-induced changes in regional cerebral blood flow in humans

Nature Communications, 2020
Could nose-to-brain pathways mediate the effects of peptides such as oxytocin (OT) on brain physiology when delivered intranasally? We address this question by contrasting two methods of intranasal administration (a standard nasal spray, and a nebulizer ...
D. Martins, N. Mazibuko, F. Zelaya, S. Vasilakopoulou, Jack Loveridge, A. Oates, S. Maltezos, S. Maltezos, Mitul A. Mehta, S. Wastling, S. Wastling, M. Howard, G. McAlonan, D. Murphy, S. Williams, A. Fotopoulou, U. Schuschnig, Y. Paloyelis   +17 more
semanticscholar   +1 more source

Oxytocin and bone

American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 2014
One of the most meaningful results recently achieved in bone research has been to reveal that the pituitary hormones have profound effect on bone, so that the pituitary-bone axis has become one of the major topics in skeletal physiology. Here, we discuss the relevant evidence about the posterior pituitary hormone oxytocin (OT), previously thought to ...
Colaianni G., Sun L., Zaidi M., Zallone A.   +3 more
openaire   +5 more sources

Oxytocin at physiological concentrations evokes adrenocorticotropin (ACTH) release from corticotrophs by increasing intracellular free calcium mobilized mainly from intracellular stores. Oxytocin displays synergistic or additive effects on ACTH-releasing factor or arginine vasopressin-induced ACTH secretion, respectively [PDF]

, 1992
The potency of oxytocin (OT) in evoking ACTH secretion by isolated, superfused rat adenohypophyseal corticotrophs and its enhancement by CRF and arginine vasopressin (AVP) were analyzed.
Dayanithi, G., Föhr, K. J., Gratzl, Manfred, Link, H.   +3 more
core   +1 more source

Oxytocin in the Male Reproductive Tract; The Therapeutic Potential of Oxytocin-Agonists and-Antagonists

Frontiers in Endocrinology, 2020
In this review, the role of oxytocin and oxytocin-like agents (acting via the oxytocin receptor and belonging to the oxytocin-family) in the male reproductive tract is considered.
Beatrix Stadler, Michael R. Whittaker, Betty Exintaris, Ralf Middendorff   +3 more
doaj   +1 more source

Systemic effects of oxytocin on male sexual activity via the spinal ejaculation generator in rats

Communicative & Integrative Biology, 2021
Oxytocin is produced in the hypothalamus and stimulates uterine contraction and milk ejection. While many people consider oxytocin to be a female hormone, it is reported that, in men, the plasma oxytocin level increases markedly after ejaculation ...
Takumi Oti, Tatsuya Sakamoto, Hirotaka Sakamoto   +2 more
doaj   +1 more source

Differential effects of MDMA and methylphenidate on social cognition [PDF]

, 2014
Social cognition is important in everyday-life social interactions. The social cognitive effects of 3,4-methylenedioxymethamphetamine (MDMA, 'ecstasy') and methylphenidate (both used for neuroenhancement and as party drugs) are largely unknown.
Crockett, Molly J., Hysek, Cédric M., Liechti, Matthias E., Quednow, Boris B., Schmid, Yasmin, Simmler, Linda D.   +5 more
core   +1 more source

Irisin‐Loaded Cerium‐Containing Mesoporous Bioactive Glass for Effective Immunomodulation and Odontogenesis of Dental Pulp Cells

Advanced Science, EarlyView.
The Irisin/Ce‐MBGNs delivery system can slowly release myokine Irisin for vital pulp therapy. Irisin/Ce‐MBGNs can enhance mitochondrial function and promote the differentiation of inflammatory macrophages toward M2‐Mφ, thereby regulating the immune response mechanism of inflamed dental pulp.
Mingxin Wang, Yuxin Yang, Jingyao Guo, Yan Chen, Xiaolin Lu, Guangdong Zhang, Yuli Wang, Minhui Yao, Yue Liu, Qian Ma   +9 more
wiley   +1 more source

Salivary Oxytocin Has Nonlinear Relationships with Trust and Reciprocity

Games, 2023
Oxytocin has been proposed to regulate human trust. Previous experiments supported this claim by demonstrating that exogenous and endogenous oxytocin is associated with trust (how much trust people place in strangers) and reciprocity (how much people ...
Sakura Arai, Motoki Watabe, Kei Kanari, Qiulu Shou, Frank Krueger, Haruto Takagishi   +5 more
doaj   +1 more source

Peptide‐Based Biomaterials as a Promising Tool for Cancer Radiotherapy

Advanced Science, EarlyView.
This review provides a systematic overview of peptide‐based biomaterials in tumor radiotherapy, covering their roles as both radiosensitizers and radiopharmaceuticals. Peptide‐based radiosensitizers are generally divided into three categories: peptides as direct radiosensitizers, peptides as carriers of radiosensitizers, and targeted‐peptide‐modified ...
Qian Wang, Xinhui Chu, Jianfeng Liu
wiley   +1 more source