Results 71 to 80 of about 182,621 (379)

Effect of oxytocin on free intracellular Ca2+ levels and progesterone release by human granulosa-lutein cells [PDF]

, 1993
Oxytocin and its receptor are found in the corpus luteum in a variety of species, including the human. In the present study we used fura-2 microfluorimetry to investigate whether activation of the oxytocin receptor of cultured human granulosa-lutein ...
Gratzl, Manfred, Link, H., Mayerhofer, Artur, Sterzik, K., Wiemann, M.   +4 more
core   +1 more source

Oxytocin Reduces Subjective Fear in Naturalistic Social Contexts via Enhancing Top‐Down Middle Cingulate Amygdala Regulation and Brain‐Wide Fear Representations

Advanced Science, EarlyView.
This double‐blind, placebo‐controlled study demonstrates that intranasal oxytocin reduces subjective fear in immersive, naturalistic social (but not non‐social) contexts. Concomitant fMRI reveals that oxytocin enhances middle cingulate activity and amygdala connectivity while it modulates network‐level connectivity and attenuates reactivity of a brain ...
Kun Fu, Shuyue Xu, Zheng Zhang, Dan Liu, Ting Xu, Yuan Zhang, Feng Zhou, Xiaodong Zhang, Chunmei Lan, Junjie Wang, Lan Wang, Jingxian He, Keith M Kendrick, Bharat Biswal, Dezhong Yao, Zhen Liang, Weihua Zhao, Benjamin Becker   +17 more
wiley   +1 more source

Intranasal Inhalation of Oxytocin Improves Face Processing in Developmental Prosopagnosia [PDF]

, 2013
Developmental prosopagnosia (DP) is characterised by a severe, lifelong impairment in face recognition. Little work has attempted to improve face processing in these individuals, but intriguingly, recent evidence suggests oxytocin can improve face ...
Bate, Sarah, Bennetts, Rachel, Burns, E., Cook, S., Duchaine, B., Hodgson, Timothy Lewis, Tree, Jeremy J.   +6 more
core  

Central mechanisms mediating the hypophagic effects of oleoylethanolamide and N-acylphosphatidylethanolamines: different lipid signals? [PDF]

, 2015
The spread of "obesity epidemic" and the poor efficacy of many anti-obesity therapies in the long-term highlight the need to develop novel efficacious therapy. This necessity stimulates a large research effort to find novel mechanisms controlling feeding
Gaetani, Silvana, Passani, Maria B., Provensi, Gustavo, Romano, Adele, Tempesta, Bianca   +4 more
core   +2 more sources

Oxytocin neurons enable social transmission of maternal behaviour

Nature, 2019
Maternal care, including by non-biological parents, is important for offspring survival1–8. Oxytocin1,2,9–15, which is released by the hypothalamic paraventricular nucleus (PVN), is a critical maternal hormone.
Ioana Carcea, Naomi López Caraballo, B. J. Marlin, Rumi Ooyama, Justin S. Riceberg, Joyce M. Mendoza Navarro, Maya Opendak, Veronica e. Diaz, Luisa Schuster, Maria I. Alvarado Torres, Harper Lethin, Daniel Ramos, Jessica L. Minder, Sebastian L. Mendoza, Chloe J. Bair-Marshall, Grace H Samadjopoulos, S. Hidema, Annegret L. Falkner, Dayu Lin, A. Mar, Y. Wadghiri, K. Nishimori, T. Kikusui, K. Mogi, R. Sullivan, R. Froemke   +25 more
semanticscholar   +1 more source

Labeled oxytocin administered via the intranasal route reaches the brain in rhesus macaques

Nature Communications, 2020
Oxytocin may have promise as a treatment for neuropsychiatric disorders. Its therapeutic effect may depend on its ability to enter the brain and bind to the oxytocin receptor.
Mary R. Lee, T. A. Shnitko, S. Blue, A. Kaucher, A. J. Winchell, David W Erikson, Kathleen A. Grant, Kathleen A. Grant, L. Leggio   +8 more
semanticscholar   +1 more source

Circular Dichroism of Oxytocin and Several Oxytocin Analogues [PDF]

Journal of Biological Chemistry, 1968
The circular dichroic spectra of oxytocin and four analogues of oxytocin are presented at several pH values in the wave length interval, 220 to 320 mµ. The analogues are 2-isoleucine- and 2-glycine-oxytocin, in which the tyrosine residues in Position 2 have been replaced by isoleucine and glycine, respectively, as well as deamino-oxytocin and deamino-2-
Sherman Beychok, Esther Breslow
openaire   +2 more sources

Cellular Adaptation to Mechanical Stress Emerges via Cell Shrinkage Triggered by Nonlinear Calcium Elevation

Advanced Science, EarlyView.
Here, a decision‐making mechanism underlying mechanical adaptation is demonstrated. This study demonstrates that cellular adaptation to mechanical stress can be induced by applying low‐amplitude stretch to cells. When the stretch reaches a critical amplitude threshold, it triggers Ca2⁺‐dependent positive feedback, which induces cholesterol efflux and ...
Zhengyan Wang, Zihan Li, Lei Wang, Haitao Zhang, Xiaoshan Yang, Lili Bao, Geng Dou, Lili Ren, Yajing Fu, Lan Li, Shengkai Gong, Yang Zhou, Feng Ding, Lu Yu, Haotian Luo, Yao Liu, Fuyang Zhang, Hui Yu, Siying Liu, Xueming Liu, Fulan Wei, Shiyu Liu   +21 more
wiley   +1 more source

Prevention of Postpartum Hemorrhage with Oxytocin versus Ergometrine Plus Oxytocin in the third stage of labor

Thai Journal of Obstetrics and Gynaecology, 2016
Objective:To evaluate the effect of the addition of intravenous ergometrine to a standard oxytocin infusion on the blood loss during vaginal delivery.Study design: Prospective, double-blinded, randomized controlled trial.Materials and methods: Three ...
Thitipun Nuamsiri, Kasemsis Kaewkiattikun   +1 more
doaj   +1 more source

The In Vitro Contractile Response of Canine Pregnant Myometrium to Oxytocin and Denaverine Hydrochloride

Biology, 2023
In pregnant bitches, the response to oxytocin and denaverine hydrochloride in dystocia management is usually poor. To better understand the effect of both drugs on myometrial contractility, the circular and longitudinal muscle layers were examined in an ...
Carolin Jungmann, Sophie-Charlotte Pyzik, Eva-Maria Packeiser, Hanna Körber, Susanne Hoppe, Gemma Mazzuoli-Weber, Sandra Goericke-Pesch   +6 more
doaj   +1 more source