Results 51 to 60 of about 22,717 (253)

Maternal infection in the context of actively managed prelabor rupture of membranes at term: An observational study

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To assess maternal infection following prelabor rupture of membranes (PROM) at term in a setting where active management is recommended, and to identify associated risk factors. Methods A retrospective cohort study was conducted including pregnant women admitted to a Portuguese tertiary care center where immediate induction of labor ...
Inês Martins, Inês Gomes Brou, Miguel Macedo, Luísa Pinto   +3 more
wiley   +1 more source

The Involvement of Oxytocin in the Subthalamic Nucleus on Relapse to Methamphetamine-Seeking Behaviour. [PDF]

PLoS ONE, 2015
The psychostimulant methamphetamine (METH) is an addictive drug of abuse. The neuropeptide oxytocin has been shown to modulate METH-related reward and METH-seeking behaviour.
Sarah Jane Baracz, Nicholas Adams Everett, Jennifer Louise Cornish   +2 more
doaj   +1 more source

Polymorphisms in Genes of Relevance for Oestrogen and Oxytocin Pathways and Risk of Barrett's Oesophagus and Oesophageal Adenocarcinoma: A Pooled Analysis from the BEACON Consortium.

PLoS ONE, 2015
BackgroundThe strong male predominance in oesophageal adenocarcinoma (OAC) and Barrett's oesophagus (BO) continues to puzzle. Hormonal influence, e.g.
Katarina Lagergren, Weronica E Ek, David Levine, Wong-Ho Chow, Leslie Bernstein, Alan G Casson, Harvey A Risch, Nicholas J Shaheen, Nigel C Bird, Brian J Reid, Douglas A Corley, Laura J Hardie, Anna H Wu, Rebecca C Fitzgerald, Paul Pharoah, Carlos Caldas, Yvonne Romero, Thomas L Vaughan, Stuart MacGregor, David Whiteman, Lars Westberg, Olof Nyren, Jesper Lagergren   +22 more
doaj   +1 more source

An external validation study of a practical scoring system for identifying patients at risk of pelvic floor dysfunction following childbirth

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To prospectively evaluate the perineal card, a risk‐based scoring system, for identifying women at increased risk of postpartum urinary incontinence (UI). Methods This prospective observational study included women without previous vaginal delivery who underwent vaginal birth at a tertiary referral center between June 2023 and ...
Martina Arcieri, Michela Segatti, Filippo Bordin, Doriana Armenise, Maria De Martino, Miriam Isola, Chiara Mattiussi, Elisa Barbui, Sara Filippin, Veronica Tius, Cristina Delneri, Valeria Dialti, Stefano Restaino, Lorenza Driul, Giuseppe Vizzielli   +14 more
wiley   +1 more source

Two Birds with One Stone: Possible Dual-role of oxytocin in the treatment of diabetes and osteoporosis

Frontiers in Endocrinology, 2015
Oxytocin, a hormone most commonly associated with labor and lactation, may have a wide variety of physiological and pathological functions, which makes oxytocin and its receptor potential targets for drug therapy.
Seham eElabd, Ismail eSabry
doaj   +1 more source

Structural basis for the activation and ligand recognition of the human oxytocin receptor

Nature Communications, 2022
Here, Waltenspühl et al. report the cryo-EM structure of active human oxytocin receptor in complex with oxytocin and with a heterotrimeric G protein, providing insights into this hormone system critically involved in the regulation of social behaviour ...
Yann Waltenspühl, Janosch Ehrenmann, Santiago Vacca, Cristian Thom, Ohad Medalia, Andreas Plückthun   +5 more
doaj   +1 more source

Mathematical Models for Possible Roles of Oxytocin and Oxytocin Receptors in Autism [PDF]

Computational and Mathematical Methods in Medicine, 2019
This paper develops mathematical models examining possible roles of oxytocin and oxytocin receptors in the development of autism. This is done by demonstrating that mathematical operations on normalized data from the Stanford study, which establishes a correspondence between severity of autism in children and their oxytocin blood levels, generate a ...
openaire   +2 more sources

Network meta‐analysis of tocolytics in preterm labor: Establishing an evidence‐based treatment hierarchy

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Background The choice of tocolytic drugs is one of the most debated aspects of preterm birth management. Objective This network meta‐analysis aimed to establish an evidence‐based hierarchy for tocolytics used in preterm labor by evaluating their efficacy in delaying delivery, safety, and neonatal outcomes.
Barbara Gardella, Chiara Cassani, Vittoria Morteo, Alessandra Marmiroli, Mattia Dominoni, Arsenio Spinillo   +5 more
wiley   +1 more source

Chronic oxytocin administration stimulates the oxytocinergic system in children with autism

Nature Communications
Clinical efficacy of intranasal administration of oxytocin is increasingly explored in autism spectrum disorder, but to date, the biological effects of chronic administration regimes on endogenous oxytocinergic function are largely unknown.
Matthijs Moerkerke, Nicky Daniels, Laura Tibermont, Tiffany Tang, Margaux Evenepoel, Stephanie Van der Donck, Edward Debbaut, Jellina Prinsen, Viktoria Chubar, Stephan Claes, Bart Vanaudenaerde, Lynn Willems, Jean Steyaert, Bart Boets, Kaat Alaerts   +14 more
doaj   +1 more source

Severe maternal and neonatal morbidity or mortality in forceps versus cesarean birth in the second stage of labor: A systematic review and meta‐analysis

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Background Approximately one in four first‐time mothers reach the second stage of labor but cannot have a spontaneous vaginal birth, necessitating an intervention such as forceps to facilitate birth. Objective This study synthesizes evidence comparing severe maternal morbidity (SMM) and neonatal morbidity or mortality (SNMM) following forceps ...
Irina I. Oltean, Abirami Kirubarajan, Giulia M. Muraca   +2 more
wiley   +1 more source