Results 31 to 40 of about 22,072 (167)
Tph2-/- female mice restore socio-sexual recognition through upregulating ERα and OTR genes in the amygdala. [PDF]
PLoS ONE, 2018 The central 5-hydroxytryptamine system impairs sociosexual behaviors and olfaction preferences in sexually naive mice. However, it remains unknown whether reproductive experiences impart an effect on the sexual olfactory preferences of female mice ...
Ying Huo +5 more
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Characterization and Expression of Oxytocin and the Oxytocin Receptor
Molecular Genetics and Metabolism, 2000 Oxytocin, a nonapeptide hormone and neurotransmitter, is expressed in a variety of tissues, as are its receptors. In vivo, oxytocin acts as a paracrine and/or autocrine mediator of multiple biological effects. These effects are exerted primarily through interactions with G-protein-coupled oxytocin/vasopressin receptors, which, via G(q) and G(i ...
H, Shojo, Y, Kaneko
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µ-Opioid receptor antagonism facilitates the anxiolytic-like effect of oxytocin in mice
Translational PsychiatryMood and anxiety disorders are leading causes of disability worldwide and are major contributors to the global burden of diseases. Neuropeptides, such as oxytocin and opioid peptides, are important for emotion regulation.
Khalin E. Nisbett +2 more
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Barriers and Breakthroughs in Targeting the Oxytocin System to Treat Alcohol Use Disorder
Frontiers in Psychiatry, 2022 Development of better treatments for alcohol use disorder (AUD) is urgently needed. One promising opportunity for this development is the potential of targeting the oxytocin peptide system.
Andrey E. Ryabinin, Yangmiao Zhang
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The interplay of oxytocin and dopaminergic system: Effects on food consumption in broiler chickens
Poultry ScienceOxytocin play a crucial physiological role in regulating feed consumption and maintaining energy homeostasis. Numerous studies have highlighted the influence of central dopaminergic systems on appetite control; however, there is a lack of information ...
Hamed Zarei +2 more
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The Involvement of Oxytocin in the Subthalamic Nucleus on Relapse to Methamphetamine-Seeking Behaviour. [PDF]
PLoS ONE, 2015 The psychostimulant methamphetamine (METH) is an addictive drug of abuse. The neuropeptide oxytocin has been shown to modulate METH-related reward and METH-seeking behaviour.
Sarah Jane Baracz +2 more
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Frontiers in Endocrinology, 2015 Oxytocin, a hormone most commonly associated with labor and lactation, may have a wide variety of physiological and pathological functions, which makes oxytocin and its receptor potential targets for drug therapy.
Seham eElabd, Ismail eSabry
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Structural basis for the activation and ligand recognition of the human oxytocin receptor
Nature Communications, 2022 Here, Waltenspühl et al. report the cryo-EM structure of active human oxytocin receptor in complex with oxytocin and with a heterotrimeric G protein, providing insights into this hormone system critically involved in the regulation of social behaviour ...
Yann Waltenspühl +5 more
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PLoS ONE, 2015 BackgroundThe strong male predominance in oesophageal adenocarcinoma (OAC) and Barrett's oesophagus (BO) continues to puzzle. Hormonal influence, e.g.
Katarina Lagergren +22 more
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Oxytocin Receptor Signaling in Vascular Function and Stroke
Frontiers in Neuroscience, 2020 The oxytocin receptor (OXTR) is a G protein-coupled receptor with a diverse repertoire of intracellular signaling pathways, which are activated in response to binding oxytocin (OXT) and a similar nonapeptide, vasopressin.
Erin C. McKay +6 more
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