Results 11 to 20 of about 22,717 (253)
Comprehensive Psychoneuroendocrinology, 2023 Purpose: In this scoping review, we synthesize the literature on oxytocin and oxytocin receptor genetic and epigenetic variation in relationship to breastfeeding, maternal caregiving behavior, and maternal mental health.
Sarah R. Weinstein +3 more
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Review of eating disorders and oxytocin receptor polymorphisms
Journal of Eating Disorders, 2021 Plain English summary Oxytocin is a chemical made in the brain that affects human behaviour in areas from anxiety, bonding right through to appetite. Oxytocin works by binding to a specific cellular receptor.
Victoria Burmester +4 more
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Oxytocin and Estrogen Receptor β in the Brain: An Overview
Frontiers in Endocrinology, 2015 Oxytocin is a neuropeptide synthesized primarily by neurons of the paraventricular and supraoptic nuclei of the hypothalamus. These neurons have axons that project into the posterior pituitary and release oxytocin into the bloodstream to promote labor ...
Alexandra eAcevedo-Rodriguez +2 more
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Endogenous oxytocin exerts anti-nociceptive and anti-inflammatory effects in rats
Communications Biology, 2022 The analgesic effect of oxytocin appears to be mediated via an oxytocin receptor and endogenous oxytocin contributes to the anti-nociception and anti-inflammatory response.
Haruki Nishimura +21 more
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The Oxytocin-Oxytocin Receptor System and Its Antagonists as Tocolytic Agents
International Journal of Endocrinology, 2011 Oxytocin, a hormone involved in numerous physiologic processes, plays a central role in the mechanisms of parturition and lactation. It acts through its receptor, which belongs to the G-protein-coupled receptor superfamily, while Gq/phospholipase C (PLC)/
Nikolaos Vrachnis +4 more
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Frontiers in Endocrinology, 2020 In this review, the role of oxytocin and oxytocin-like agents (acting via the oxytocin receptor and belonging to the oxytocin-family) in the male reproductive tract is considered.
Beatrix Stadler +3 more
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Prolactin and oxytocin: potential targets for migraine treatment
The Journal of Headache and Pain, 2023 Migraine is a severe neurovascular disorder of which the pathophysiology is not yet fully understood. Besides the role of inflammatory mediators that interact with the trigeminovascular system, cyclic fluctuations in sex steroid hormones are involved in ...
Anna K. Szewczyk +18 more
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The Structure and Regulation of the Oxytocin Receptor [PDF]
Experimental Physiology, 2001 The oxytocin receptor (OTR) is part of an ancient hormone system expressed in diverse phyla in relation to acute reproductive smooth muscle responses, such as egg‐laying, birth, or milk letdown. The regulation of the OTR gene, while correlating with steroid levels in vivo, remains elusive.
Ivell, R. +9 more
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Oxytocin reduces adipose tissue inflammation in obese mice
Lipids in Health and Disease, 2020 Background Obesity and adipose tissue expansion is characterized by a chronic state of systemic inflammation that contributes to disease. The neuropeptide, oxytocin, working through its receptor has been shown to attenuate inflammation in sepsis, wound ...
Angela Szeto +4 more
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An analgesic pathway from parvocellular oxytocin neurons to the periaqueductal gray in rats
Nature Communications, 2023 The hypothalamic neuropeptide oxytocin exerts analgesic effects, but the underlying pathways remain largely elusive. Here, the authors describe an analgesic pathway formed by oxytocin neurons projecting to the periaqueductal grey, where axonally released
Mai Iwasaki +30 more
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