Results 21 to 30 of about 22,072 (167)

The oxytocin/vasopressin receptor antagonist atosiban delays the gastric emptying of a semisolid meal compared to saline in human

BMC Gastroenterology, 2006
Background Oxytocin is released in response to a meal. Further, mRNA for oxytocin and its receptor have been found throughout the gastrointestinal (GI) tract.
Ekberg Olle, Björgell Ola, Ohlsson Bodil, Darwiche Gassan   +3 more
doaj   +1 more source

Oxytocin: A developmental journey

Comprehensive Psychoneuroendocrinology, 2023
The neuropeptide hormone oxytocin is involved in many processes in our bodies, linking our social lives to our internal states. I started out my career studying primate families, an interest that expanded into the role of oxytocin in family-oriented ...
Karen L. Bales
doaj   +1 more source

Pyrazolsulfonamide Agonists of Oxytocin Receptor [PDF]

ACS Medicinal Chemistry Letters, 2014
Title: Pyrazolsulfonamide Agonists of Oxytocin Receptor Patent/Patent Application Number: WO 2014/111356 A1 Publication date: July 24, 2014 Priority Application: EP 2013-151632 Priority date: January 17, 2013 Inventors: Bissantz, C.; Grundschober, C.; Nettekoven, M.; Plancher, J.-M.; Vifian, W. Assignee Company: Hoffmann-La Roche, Inc.
openaire   +2 more sources

Expression and activation of the oxytocin receptor in airway smooth muscle cells: Regulation by TNFα and IL-13

Respiratory Research, 2010
Background During pregnancy asthma may remain stable, improve or worsen. The factors underlying the deleterious effect of pregnancy on asthma remain unknown.
Siddiqui Salman, Zhao Hengjiang, Cooper Philip R, Baidouri Hasna, Sims Michael W, Keslacy Stefan, Jain Deepika, Liu Veronica, Li Katherine, Huang Chris, Syed Farhat, Amrani Yassine, Brightling Christopher E, Griswold Don, Li Lily, Panettieri Reynold A   +15 more
doaj   +1 more source

Involvement of Hyperpolarization-Activated Cyclic Nucleotide-Gated Channel 3 in Oxytocin Neuronal Activity in Lactating Rats With Pup Deprivation

ASN Neuro, 2020
Oxytocin, a hypothalamic neuropeptide essential for breastfeeding, is mainly produced in oxytocin neurons in the supraoptic nucleus (SON) and paraventricular nucleus.
Dongyang Li, Haitao Liu, Xiaoyu Liu, Hongyang Wang, Tong Li, Xiaoran Wang, Shuwei Jia, Ping Wang, Yu-Feng Wang   +8 more
doaj   +1 more source

Cerebellar damage with inflammation upregulates oxytocin receptor expression in Bergmann Glia

Molecular Brain
The cerebellum plays an important role in cognitive and social functioning. Childhood damage in the cerebellum increases the risk of autism spectrum disorder. Cerebellar inflammation induces social avoidance in mice.
Ayumu Inutsuka, Aisa Hattori, Masahide Yoshida, Yuki Takayanagi, Tatsushi Onaka   +4 more
doaj   +1 more source

Moxie begets MOXI: The journey to a novel hypothesis about Mu-opioid and OXytocin system Interactions

Comprehensive Psychoneuroendocrinology
This narrative review summarizes the early life of the author, Khalin E. Nisbett, and highlights the factors that led to her career in research and her development of two novel research hypotheses: the Mu-opioid and OXytocin system Interaction (MOXI ...
Khalin E. Nisbett
doaj   +1 more source

Neurosteroid involvement in threatened preterm labour

Endocrinology, Diabetes & Metabolism, 2021
Introduction The neurosteroid allopregnanolone modulates oxytocin expression in the brain, and its effects arise from its action on the GABAA receptor. Whether neurosteroid levels and the function of the GABAA receptor are involved in the risk of preterm
Sahruh Turkmen, Torbjörn Bäckström, Yvonne Kangas Flodin, Marie Bixo   +3 more
doaj   +1 more source

Quantitative cellular-resolution map of the oxytocin receptor in postnatally developing mouse brains

Nature Communications, 2020
The oxytocin receptor plays an important role in establishing mature neural circuits for social behavior during the early postnatal period. Here, the authors develop digital reference brains for different postnatal ages and provide a quantitative brain ...
Kyra T. Newmaster, Zachary T. Nolan, Uree Chon, Daniel J. Vanselow, Abigael R. Weit, Manal Tabbaa, Shizu Hidema, Katsuhiko Nishimori, Elizabeth A. D. Hammock, Yongsoo Kim   +9 more
doaj   +1 more source

Oxytocin alleviates liver fibrosis via hepatic macrophages

JHEP Reports
Background & Aims: Previous studies demonstrated oxytocin treatment effectiveness in reducing mortality and reversing liver fibrosis in mice. However, the underlying mechanism remains obscure, given the absence of oxytocin receptor expression in ...
Xiangyu Zhai, Hao Zhang, Zhijia Xia, Mingkun Liu, Gang Du, Zhengchen Jiang, Huaxin Zhou, Dan Luo, Dandan Dou, Jingxin Li, Wei Wang, Xiaosong Li, Bin Jin   +12 more
doaj   +1 more source