Results 71 to 80 of about 535,314 (143)

Nanostructured drug delivery systems for posterior segment eye diseases: Strategies to defy ocular barriers

BMEMat, Volume 4, Issue 1, March 2026.
Efficient drug delivery to the posterior segment of the eye has long been a challenging issue due to the complex ocular barriers. The review focuses on the promise held by nanoplatforms for barrier penetration and the key mechanisms involved, also highlighting their advantages in achieving efficient drug delivery and superior treatment of PSEDs ...
Yifan Shen, Ying Yao, Yan Zhang, Xinyu Shi, Ling Bai, Yang Zhong, Yan Zhang, Kun Zhang   +7 more
wiley   +1 more source

Evaluación de puntos hiperreflectivos y de las capas retinianas externas en imágenes de SD-OCT de pacientes con edema macular secundario a oclusión venosa retiniana, tratados mediante el implante intravítreo de dexametasona (Ozurdex) [PDF]

, 2020
OBJETIVOS DEL ESTUDIO1. Caracterizar, en pacientes de nuestro entorno afectos de edema macular (EM) secundario a oclusión venosa retiniana (OVR), la mejor agudeza visual corregida (MAVC) y los hallazgos microestructurales retinianos observables en ...
Almenara Michelena, Cristina, Ascaso Puyuelo, Francisco Javier, Cristóbal Bescós, José Ángel   +2 more
core  

Intravitreal dexamethasone implant (Ozurdex®) serial evaluation with ocular ultrasound [PDF]

, 2023
Objetivo: Comparação dos achados ultrassonográficos e das medidas do implante de Ozurdex® na cavidade vítrea ao longo do tempo. Métodos: Olhos submetidos a implante intravítreo de Ozurdex® foram avaliado no mesmo dia do procedimento (D0) e reavaliados a ...
Pellegrini, Gabriela Assumpção Brito Pereira [UNIFESP]
core  

Implantable Drug Delivery Systems for Skeletal Muscles and Eyes

Advanced NanoBiomed Research, Volume 6, Issue 2, February 2026.
This review highlights the different types of recent implantable drug delivery systems (IDDS) fabricated for a use with skeletal muscles, and with eyes. It presents the developments already made and the current research directions, showing the evolution of IDDS and their great diversity.
Serge Ostrovidov, Murugan Ramalingam, Hongkai Wu, Toshinori Fujie, Yukinari Nakamura, Takeshi Hori, Yuji Nashimoto, Xuetao Shi, Hirokazu Kaji   +8 more
wiley   +1 more source

Change in macular thickness in a case of refractory diabetic macular edema with dexamethasone intravitreal implant in comparison to intravitreal bevacizumab: A case report

Indian Journal of Ophthalmology, 2012
We report on the significant improvement of central macular thickness in a case of clinically significant macular edema after dexamethasone 0.7 mg sustained-release intravitreal implant (Ozurdex®; Allergan, Inc, Irvine, CA, USA).
Ashish Sharma, Rangasamy J Madhusudhan, Vidhya Nadahalli, Shreekant A Damgude, Selva K Sundaramoorthy   +4 more
doaj   +1 more source

Selective Laser Sintering 3D Printing of Drug‐Loaded Intravitreal Implants

Advanced Functional Materials, Volume 36, Issue 4, 12 January 2026.
Selective laser sintering enables the fabrication of biodegradable and biocompatible intravitreal implants with tunable microstructures for sustained drug delivery. By modulating laser scanning speed, the polymer matrix architecture is engineered to control the release kinetics of dexamethasone and riboflavin over several months. This approach offers a
Iria Seoane‐Viaño, Carlos Bendicho‐Lavilla, Haya Alfassam, Bárbara Blanco‐Fernández, Abdul W. Basit, Francisco J. Otero‐Espinar   +5 more
wiley   +1 more source

Efficacy of intravitreal injection of the dexamethasone intravitreal implant Ozurdex® in treatment of patients with refractory diabetic macular edema of different optical coherence tomography patterns [PDF]

精准医学杂志
Objective To investigate the efficacy of intravitreal injection of Ozurdex® in the treatment of refractory diabetic macular edema (DME) with different optical coherence tomography (OCT) patterns.
WANG Yibo, MENG Xuxia, LIU Penghui, YANG Jing
doaj   +1 more source

Methotrexate‐Loaded Liposomal Formulation Enables 6‐Week Sustained Intraocular Therapeutic Drug Release in a Porcine Model

Advanced Healthcare Materials, Volume 15, Issue 1, 9 January 2026.
A liposomal formulation for methotrexate enables minimally invasive, sustained intraocular drug delivery for over six weeks with a single injection. Developed for treating intraocular diseases like lymphoma and PVR, it offers excellent biocompatibility in vivo in a porcine model.
Maximilian Hammer, Lea Skrzypczyk, Sabrina Wohlfart, Bryan Calder Ackermann, Ludwig Geisweid, Simon William Pohl, Margarita Karaivanova, Jonathan Herth, Victor Aristide Augustin, Alexander Studier‐Fischer, Tina Sackmann, Leon Kaulen, Anna Steyer, Walter Mier, David H Steel, Kanmin Xue, Gerd Uwe Auffarth, Philipp Uhl   +17 more
wiley   +1 more source

Intravitreal Injection of Dexamethasone Implant in Serous Macular Detachment Associated with Waldenström's Disease

Case Reports in Ophthalmology, 2013
Purpose: To evaluate the efficacy of one intravitreal injection of dexamethasone (Ozurdex®; Allergan, Inc., Irvine, Calif., USA) in serous macular detachment (SMD) of one eye, associated with bilateral central retinal vein occlusion (CRVO) in a patient ...
Vito Fenicia, Marco Balestrieri, Andrea Perdicchi, Giorgia Maraone, Santi Maria Recupero   +4 more
doaj   +1 more source

Acute Retinal Detachment Following Ozurdex Implant in a Nonvitrectomized Eye

Case Reports in Ophthalmological Medicine, Volume 2026, Issue 1, 2026.
Intravitreal injection (IVI) of antivascular endothelial growth factors and dexamethasone implants are among the most performed procedures in ophthalmology, as they are used to treat various retinal diseases. Although considered safe, some rare but sight‐threatening complications can occur, like endophthalmitis and retinal detachment. Here, we report a
Abdullah Alkhamees, Khaled Alsabah, Alexander Bialasiewicz   +2 more
wiley   +1 more source