Results 81 to 90 of about 535,314 (143)

Влияние интравитреального введения пролонгированных кортикостероидов на динамику внутриглазного давления [PDF]

, 2021
PURPOSE. To analyze the effects of intravitreal injections of prolonged corticosteroids (Ozurdex®) on intraocular pressure (IOP).METHODS. The study involved 330 patients (142 men, 188 women aged 54.5 (40 to 63) years who received 399 intravitreal ...
И. А. Лоскутов, Д. А. Аслан, Е. Н. Хомякова, D. A. Aslan, E. N. Khomyakova, I. A. Loskutov   +5 more
core   +1 more source

Toward Precision Medicine: Gene Therapy Applications in the Management of Uveal Melanoma

Cancer Reports, Volume 8, Issue 12, December 2025.
ABSTRACT Background Uveal melanoma (UM) is the prevailing malignant tumor that develops within the eye in adults, and it has a bleak outlook because of the few treatment choices available and the high likelihood of returning after treatment. Currently, surgical intervention, radiation therapy, and a combination of both modalities are available ...
Alireza Azani, Vahid Ghassemifar, Zahra Mehrdad, Maryam Saberivand, Anahid Bagheripour, Safa Tahmasebi, Hossein Gharedaghi, Malihe Sharafi, Hassan Foroozand, Mohammad Saeed Soleimani Meigoli, Saba Pourali, Arash Salmaninejad, Faeze Ahmadi Beni, Qumars Behfar   +13 more
wiley   +1 more source

“Magic Bullet”: Eccentric Macular Hole as a Complication from Dexamethasone Implant Insertion

Case Reports in Ophthalmological Medicine, 2016
Introduction. Intravitreal drug injections and implants are generally safe but do carry some risk, from both the procedure itself and adverse effects of the medications. We report a case of an eccentric macular hole after dexamethasone implant (Ozurdex®)
Logan Christensen, Riley Sanders, Jeffrey Olson   +2 more
doaj   +1 more source

Resolution of Persistent Cystoid Macular Edema due to Central Retinal Vein Occlusion in a Vitrectomized Eye following Intravitreal Implant of Dexamethasone 0.7 mg

Case Reports in Ophthalmology, 2012
We report the case of a 62-year-old woman with a history of vitreoretinal surgery for vitreous hemorrhage secondary to central retinal vein occlusion (CRVO).
Michele Reibaldi, Andrea Russo, Marco Zagari, Mario Toro, Vittorio De Grande, Valentina Cifalinò, Stefania Rametta, Salvatore Faro, Antonio Longo   +8 more
doaj   +1 more source

Surgical Management of Complications after Dexamethasone Implant

Case Reports in Ophthalmological Medicine, 2020
Purpose. To report surgical management of ocular complications occurred after dexamethasone (DEX) implant (Ozurdex®) injection. Methods. Retrospective interventional case series. Results.
Giancarlo Sborgia, Alfredo Niro, Francesco D’Oria, Alessandra Galeone, Luigi Sborgia, Francesco Boscia, Alessandra Sborgia, Giovanni Alessio   +7 more
doaj   +1 more source

Application of Machine Learning to Discriminate Photoreceptor Cell Species in Xenotransplanted Chimeric Retinas

Clinical and Translational Science, Volume 18, Issue 12, December 2025.
ABSTRACT Photoreceptor transplantation is being studied to restore visual function in retinal diseases causing blindness, including age‐related macular degeneration, hereditary eye diseases, and traumatic retinopathy. Preclinical studies often involve delivering exogenous human photoreceptor cells into animal models' retinas.
Kang V. Li, Annabelle Pan, Ying V. Liu, Bani Antonio‐Aguirre, Joyce Wang, McKaily Adams, Christina McNerney, Sai Bo Bo Tun, Kenneth Jimenez, Yuchen Lu, Zhuolin Li, Minda McNally, Veluchamy A. Barathi, Robert J. Johnston Jr., Mandeep S. Singh   +14 more
wiley   +1 more source

Stimuli‐responsive systems: A focus on controlled drug delivery for posterior segment ocular disease

Responsive Materials, Volume 3, Issue 4, November 2025.
This review highlights recent advances in stimuli‐responsive drug delivery for posterior segment diseases, focusing on mechanisms and potential. It also explores mechanically interlocked molecules and bioorthogonal reactions as novel approaches. Challenges and future perspectives are discussed, aiming to bridge the gap between research and clinical ...
Chengzhi Zhang, Jiayi Hou, Yameng Zhao, Yiwen Wang, Kexin Wang, Siyu Li, Yange Wang, Jiehao Zhang, Shenao Ding, Chenxu Zhang, Zongming Song, Ye Tao   +11 more
wiley   +1 more source

Cross-ocular therapeutic response to unilateral dexamethasone implant in pseudophakic macular edema

Indian Journal of Ophthalmology. Case Reports
Pseudophakic macular edema (PME) commonly responds to topical anti-inflammatory therapy, although refractory cases may require sustained corticosteroid delivery. We describe a 66-year-old male with bilateral PME who received an intravitreal dexamethasone
Sonal Paliwal, Prerna Upadhyaya, Sanjiti Arya   +2 more
doaj   +1 more source

Acute-Onset Endophthalmitis Caused by Alloiococcus otitidis following a Dexamethasone Intravitreal Implant

Case Reports in Ophthalmology, 2013
Purpose: To report the first case of acute endophthalmitis caused by Alloiococcus otitidis after a dexamethasone intravitreal implant. Methods: A 74-year-old female was treated with intravitreal Ozurdex® in her left eye for central retinal vein occlusion
Tizana Marchino, José I. Vela, Francisca Bassaganyas, Saskia Sánchez, José A. Buil   +4 more
doaj   +1 more source

Magnetically Controllable and Degradable Milliscale Swimmers as Intraocular Drug Implants

Advanced Science, Volume 12, Issue 34, September 11, 2025.
Magnetically controllable degradable milliscale swimmers (MDMS) offer a promising alternative to commercial intraocular drug implants, reducing complications like implant dislocation and uncontrolled drug release. MDMS achieve high velocities in ocular environments, enable real‐time imaging, and deliver drugs effectively without disrupting retinal ...
Erdost Yildiz, Ugur Bozuyuk, Eray Yildiz, Fan Wang, Mertcan Han, Alp Can Karacakol, Devin Sheehan, Yan Yu, Metin Sitti   +8 more
wiley   +1 more source