Results 91 to 100 of about 15,888 (201)

Deciphering the Transcriptomic Signatures of Aging Across Organs in Mice

Aging Cell, Volume 25, Issue 2, February 2026.
Comprehensive transcriptomic profiling of eight mouse organs across six ages reveals how aging reshapes biological processes. Trajectory and network analyses distinguish shared and organ‐specific signatures, charting the molecular landscape of systemic aging.
Sarah Morsy, Enzo Scifo, Kan Xie, Kristina Schaaf, Jenny Russ, Stefan Paulusch, Elena De Domenico, Paolo Salomoni, Daniele Bano, Dan Ehninger   +9 more
wiley   +1 more source

Prenatal exposure to gestational diabetes mellitus increases developmental defects in the enamel of offspring.

PLoS ONE, 2019
BACKGROUND AND OBJECTIVE:Gestational diabetes mellitus (GDM) is associated with short- and long-term maternal and perinatal repercussions. Our objective was to evaluate the long-term consequences of intrauterine exposure to hyperglycemia on Developmental
Tawana Pascon, Angélica M P Barbosa, Rita C L Cordeiro, Diego G Bussaneli, Caroline B Prudencio, Sthefanie K Nunes, Fabiane A Pinheiro, Grasiela Bossolan, Leandro G Oliveira, Iracema M P Calderon, Gabriela Marini, Marilza V C Rudge   +11 more
doaj   +1 more source

p,p′-DDE fails to reduce the competitive reproductive fitness in Nigerian male guppies

Ecotoxicology and Environmental Safety, 2006
The ecologically highly important effect of intermale competition is assessed here in a new approach to evaluating endocrine disruption at the population level. A guppy (Poecilia reticulata) male exposed to the antiandrogenic DDT metabolite p,p'-DDE competed against an unexposed male for the opportunity to fertilize a female.
Thomas, Kristensen, Erik, Baatrup, Mark, Bayley   +2 more
openaire   +2 more sources

Determinación de compuetos organoclorados y porfirinas en huevos de pagaza piconegra [PDF]

, 2017
Master Universitario en Investigación Básica y Aplicada en Recursos Cinegéticos. Trabajo de fin de master. Tema: Toxicología en Fauna Silvestre.En el presente estudio se ha definido la presencia y concentración de compuestos organoclorados y PCBs en 97 ...
Pérez de Vargas, Ana
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Levels and enantiomeric signatures of methyl sulfonyl PCB and DDE metabolites in livers of harbor porpoises (Phocoena phocoena) from the southern North Sea [PDF]

, 2003
The concentration of 26 methyl sulfonyl metabolites of polychlorinated biphenyls (MeSO2-PCBs) and of p,p'-DDE (MeSO2-DDE) were determined in 19 liver samples from harbor porpoises (Phocoena phocoena) stranded between 1997 and 2000 on the Belgian and ...
Berggren P., Bergman, Boon J. P., Boon J. P., Boon J. P., Brandt I., Chu S. G., Chu S. G., Chu S. G., Covaci A., Ellerichmann T., Haraguchi K., Haraguchi K., Harner T., Hühnerfuss H., Hühnerfuss H., Jensen S., Kaiser K. L. E., Karlson K., Koake G., Larsen G. L., Larsson C., Letcher R. J., Letcher R. J., Letcher R. J., Nagayama J., Nezel T., Tanabe S., Troisi G. M., Troisi G. M., Weistrand C., Wiberg K.   +31 more
core   +1 more source

Clinical and Molecular Effect of the Anti–IL‐18 Antibody Aletekitug in Adults With Atopic Dermatitis

Allergy, Volume 81, Issue 2, Page 539-551, February 2026.
At Week 12, aletekitug was associated with a −68.3% percentage change from baseline in EASI score. Aletekitug improved the transcriptional profile of lesional skin towards that of non‐lesional skin at Week 4 and Week 12. Aletekitug was well‐tolerated; no serious adverse event or death occurred, and no patient withdrew due to an adverse event.
Joanne Ellis, Léa Fortunato, Hannah Wajdner, Ester Del Duca, Joanna Barnard, Joanna C. Betts, Swaroop Bose, John Browning, Núria Buil‐Bruna, Scott Van Buren, Eden David, Scott Dinehart, Puneet Dhawan, Yeriel Estrada, Parima Ghafoori, Kiranmai Gumireddy, Zhenghong Li, Wei Jing Loo, Fiona Lovegrove, Jenny Lowe, Lawrence Charles Parish, Will Powley, Naveen Prasad, Joel Correa Da Rosa, Marieta Ruseva, Neda Shokrian, Farhat Syed, Chun‐Hang Tang, Gabriel K. Wong, John B. Kelly, Nicolas Wisniacki, Iain Uings, Emma Guttman‐Yassky   +32 more
wiley   +1 more source

Avian Cholera in a Bald Eagle from Ohio [PDF]

, 1972
Author Institution: Patuxent Wildlife Research Center, Laurel, Maryland 20810, and Department of Veterinary Science (J. A. N.), University of Maryland, College Park, Maryland 20742Avian cholera (Pasteurella multocida) infection was diagnosed in an adult ...
Locke, L. N., Mulhern, B. M., Newman, J. A.   +2 more
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White–Sutton Syndrome: Insight of an Italian Cohort of 19 Subjects

Clinical Genetics, Volume 109, Issue 2, Page 335-340, February 2026.
New insights into White–Sutton syndrome with a collection of 19 Italian patients. Due to its complexity, we stress the importance of a systematic evaluation following the diagnosis and a thoughtful management of patients. Preliminary genotype–phenotype correlation analysis suggests the association between disruptive splicing variants and more severe ...
Anna Facchini, Maria Pina Concas, Stefania Zampieri, Iris Scala, Claudio Graziano, Anna Maria Innoceta, Marina Trivisano, Angela De Dominicis, Gabriele Trimarchi, Livia Garavelli, Margherita Baldassarri, Ilaria De Maggio, Francesca Mari, Donatella Greco, Paolo Gasparini   +14 more
wiley   +1 more source

Endocrine disruptors and spontaneous premature labor: a case control study

Environmental Health, 2007
Background Premature labor is a poorly understood condition. Estrogen is thought to play a key role and therefore the labor process may be affected by endocrine disruptors.
Swaby Cheryl, Jarrell John J, Wood Stephen L, Chan Sui   +3 more
doaj   +1 more source

Steroid Hormones and Endocrine Disruptors: Recent Advances in Receptor–Mediated Actions [PDF]

, 2001
It has been accepted that receptor-mediated action of steroid hormones depends on both the receptor and the hormonal level. The mechanism of transcription by steroid receptors is mediated by cofactors, which function as co-activators or co-repressors,
Indarto, Dono, Izawa, Masao
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