Results 21 to 30 of about 844,522 (250)

Sex Differences on Mitotane Concentration and Treatment Outcome in Patients with Adrenocortical Carcinoma

open access: yesLife, 2021
(1) Background: In clinical settings, data regarding sex are rarely investigated. In women, factors such as body size and composition, hormonal variations, metabolism, and access to care systems and therapy could strongly influence the pharmacological ...
Sarah Allegra   +7 more
doaj   +1 more source

Effects of organochlorine exposure on male reproductive disorders in an electronic waste area of South China

open access: yesEnvironment International, 2021
Several studies suggest that organochlorine exposure can affect male reproductive functions, causing poor semen quality, endocrine disruption, or dysregulation of thyroid hormones.
Bi-gui Lin   +11 more
doaj   +1 more source

Sex-Based Evaluation of Lipid Profile in Postoperative Adjuvant Mitotane Treatment for Adrenocortical Carcinoma

open access: yesBiomedicines, 2022
Background: A wide interindividual variability in mitotane concentrations and treatment-related dyslipidemia have been reported. Here, we aimed to underline the sex-related differences in the lipid profile in patients that underwent radical surgery of ...
Sarah Allegra   +7 more
doaj   +1 more source

Excretion Rate and Accumulating Rate of p, p'-DDE in Beijing Resident during Consecutive Lactation

open access: yesYankuang ceshi, 2021
BACKGROUND Monitoring of p, p'-DDE in breast milk was a significant way to evaluate the p, p'-DDE accumulation level in human beings within a short-term and calculate daily intake for infants.
SONG Shu-ling, PAN Meng, MA Xiao-dong
doaj   +1 more source

Effects of p,p'-DDE on H19 DMR methylation and insulin secretion of INS-1 cells

open access: yes环境与职业医学, 2022
BackgroundDiabetes is a major threat to public health across the world. Studies have shown that exposure to p,p'-dichlorodiphenyldichloroethylene (p,p'-DDE) is closely related to the occurrence of type 2 diabetes mellitus. However, the relevant molecular
Yanqiu ZONG   +5 more
doaj   +1 more source

Effects of o,p’-DDE, a Mitotane Metabolite, in an Adrenocortical Carcinoma Cell Line

open access: yesPharmaceuticals, 2022
In South Brazil, the incidence of pediatric adrenocortical carcinoma (ACC) is higher than in other regions and countries worldwide. The ACC treatment includes therapy with mitotane, the only adrenolytic drug approved by the FDA.
Camila Bach   +4 more
doaj   +1 more source

Chronic DDE Exposure Modifies Mitochondrial Respiration during Differentiation of Human Adipose-Derived Mesenchymal Stem Cells into Mature Adipocytes

open access: yesBiomolecules, 2021
The contribution of environmental pollutants to the obesity pandemic is still not yet fully recognized. Elucidating possible cellular and molecular mechanisms of their effects is of high importance.
Iva Kladnicka   +9 more
doaj   +1 more source

Effect of Biochar on Phytoextraction of Persistent Organic Pollutants

open access: yesTurkish Journal of Agriculture: Food Science and Technology, 2019
Cucurbita pepo spp. pepo has a unique ability to phytoextract Persistent Organic Pollutants (POPs) such as p,p’-DDE from the contaminated soil to plant compartments. Although the uptake mechanism of the POPs by the plants still remains unknown, p,p’-DDE
Pınar Sevim Elibol
doaj   +1 more source

Levels and Determinants of DDT and DDE Exposure in the VHEMBE Cohort. [PDF]

open access: yes, 2017
BackgroundAlthough indoor residual spraying (IRS) is an effective tool for malaria control, its use contributes to high insecticide exposure in sprayed communities and raises concerns about possible unintended health effects.ObjectiveThe Venda Health ...
Barr, Dana Boyd   +7 more
core   +4 more sources

Home - About - Disclaimer - Privacy