Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Hiperinsulinismo endógeno diagnosticado como epilepsia
Revista Colombiana de Endocrinología, Diabetes y Metabolismo, 2017 El insulinoma es la neoplasia endocrina más común del páncreas, 90% de ellos son benignos, su incidencia es de 4 por 1 millón de personas al año y representa el 1% al 2% de todas las neoplasias pancreáticas.
Alejandro Pinzón Tovar +1 more
doaj +1 more source
Cuantificación de la masa de células beta en páncreas de ratas diabéticas sometidas a cirugía bariátrica [PDF]
, 2015 Bariatric surgery includes a series of surgical techniques aimed at the decrease in caloric intake or absorption of nutrients through the digestive tract via surgical alteration. This is an important therapeutic tool against obesity and currently is also
España-Domínguez, Carolina
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The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
RELATIONS AND LINKS BETWEEN EXOCRINE AND ENDOCRINE PANCREAS
Revista de la Sociedad Argentina de Diabetes, 2020 The endocrine and exocrine pancreas come from the same embryonic button and live in the same organ: the pancreas. However, in practice it is usual to approach endocrine diseases, such as diabetes mellitus, and exocrine ones, such as pancreatitis, in a ...
Luis Grosembacher
doaj +1 more source
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
FEBS Letters, EarlyView.CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source
In vitro analysis of apoptosis in hepatic stellate cells cultured under steatogenic conditions
Annals of HepatologyIntroduction and Objectives: Hepatic stellate cells (HSC) are responsible for the development of fibrosis during chronic liver disease. Cell death is among the most common cellular causes of increased tissue damage. From the different types of cell death,
Adriana Campos-Espinosa +3 more
doaj +1 more source
Hemoperitoneo espontáneo secundario a rotura de pseudoquiste pancreático: una causa inusual de muerte inesperada [PDF]
, 2015 Presentamos un caso de fallecimiento por hemoperitoneo masivo espontáneo como complicación tardía de un pseudoquiste pancreático de evolución tórpida. Se trata de una causa muy infrecuente de hemoperitoneo espontáneo en la literatura médica. Se describen
Aguilera Tapia, Beatriz +1 more
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Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Cirugía derivativa más radioterapia intraoperatoria y externa en el carcinoma de páncreas localizado e irresecable [PDF]
, 1993 Presentamos una serie de 25 casos de carcinomas de páncreas localmente avanzados e irresecables, sin metástasis a distancia, tratados con cirugía derivativa, radioterapia intraoperatoria e irradiación externa: 18 tumores de cabeza (16 con ictericia ...
Balen, E. (Enrique) +8 more
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