Results 31 to 40 of about 466,613 (249)
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Hiperinsulinismo endógeno diagnosticado como epilepsia
Revista Colombiana de Endocrinología, Diabetes y Metabolismo, 2017 El insulinoma es la neoplasia endocrina más común del páncreas, 90% de ellos son benignos, su incidencia es de 4 por 1 millón de personas al año y representa el 1% al 2% de todas las neoplasias pancreáticas.
Alejandro Pinzón Tovar +1 more
doaj +1 more source
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
FEBS Letters, EarlyView.CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source
RELATIONS AND LINKS BETWEEN EXOCRINE AND ENDOCRINE PANCREAS
Revista de la Sociedad Argentina de Diabetes, 2020 The endocrine and exocrine pancreas come from the same embryonic button and live in the same organ: the pancreas. However, in practice it is usual to approach endocrine diseases, such as diabetes mellitus, and exocrine ones, such as pancreatitis, in a ...
Luis Grosembacher
doaj +1 more source
Possible relació entre el consum de lactis i la mutació d'un gen cancerigen [PDF]
, 2007 Un article científic publicat al número de juliol de la revista anglesa Journal of Epidemiology and Community Health suggereix que pot existir una relació entre la ingesta de productes lactis i l'aparició de mutacions en un gen important al càncer de ...
Porta, Miquel,
core +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
In vitro analysis of apoptosis in hepatic stellate cells cultured under steatogenic conditions
Annals of HepatologyIntroduction and Objectives: Hepatic stellate cells (HSC) are responsible for the development of fibrosis during chronic liver disease. Cell death is among the most common cellular causes of increased tissue damage. From the different types of cell death,
Adriana Campos-Espinosa +3 more
doaj +1 more source
Pancreatitis aguda necrótico-hemorrágica: propósito de dos autopsias judiciales [PDF]
, 2015 La pancreatitis necrótico-hemorrágica, es una complicación inusual y altamente mortal en los casos de inflamación de la glándula pancreática. El diagnóstico es de sospecha clínica apoyado por pruebas de laboratorio y de radiodiagnóstico.
Luis García, María José de
core +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Cirugía derivativa más radioterapia intraoperatoria y externa en el carcinoma de páncreas localizado e irresecable [PDF]
, 1993 Presentamos una serie de 25 casos de carcinomas de páncreas localmente avanzados e irresecables, sin metástasis a distancia, tratados con cirugía derivativa, radioterapia intraoperatoria e irradiación externa: 18 tumores de cabeza (16 con ictericia ...
Balen, E. (Enrique) +8 more
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