Results 121 to 130 of about 34,845 (214)

Neuromodulation using Bioelectronics-enabled therapies to combat insulin resistance and its comorbidities. [PDF]

J Diabetes Metab Disord
Mekki YM, Park J, Alzaareer Z, Hussain Z, Gulzar A, Elzouki A, Güemes A, Zughaier SM.   +7 more
europepmc   +1 more source

Recent Perspectives on Phytochemical Profile, Pharmacological Activities, and Industrial Applications of Guava (Psidium guajava)

Food Safety and Health, EarlyView.
Psidium guajava leaves contain potent bioactive compounds like quercetin, myricetin, and triterpenoids that show antioxidant, antidiabetic, anti‐inflammatory, and anticancer effects. They act by modulating NF‐κB, PPARγ, and α‐glucosidase and by inducing apoptosis and cell cycle arrest.
Muhammad Waqar, Sehrish Jabbar, Qudrat Ullah, Farhang Hameed Awlqadr, Muhammad Tayyab Arshad, Md. Sakhawot Hossain, Sammra Maqsood, Ali Ikram, Ammar Ahmad Khan, Worawan Panpipat, Manat Chaijan   +10 more
wiley   +1 more source

Integral Sliding Mode Control with Dual-Hormone for an Artificial Pancreas

ENP Engineering Science Journal
Low concentration of glucose, “hypoglycemia” is the most critical complication for type 1 diabetes patients, may lead to coma or death. For this purpose, a dual-hormonal control of glycaemia is required, using insulin to recover the period of ...
Souassane Mahour, Mohamed Tadjine, Messaoud Chakir   +2 more
doaj  

Case Report: Robotic-assisted laparoscopic primary repair for pancreaticoduodenal grade V injury in a pediatric patient. [PDF]

Front Pediatr
Liang Z, Wang X, Lan M, Xu X, Zeng J.
europepmc   +1 more source

A multilevel perspective on MSH6‐associated Lynch syndrome: Integrating molecular, biological, and clinical insights

International Journal of Cancer, EarlyView.
Abstract Lynch syndrome (LS) is the most common hereditary colorectal cancer syndrome, caused by a germline pathogenic variant in one of the mismatch repair (MMR) genes. Among these, MSH6‐associated LS represents a distinct subtype with unique molecular and clinical characteristics.
Salwa Ben Yahia, Anne‐Sophie van der Werf‐'t Lam, Madalina Cabuta, Maartje Nielsen, Noah C. Helderman   +4 more
wiley   +1 more source

Case Report: Bezoar in allograft duodenum-rare cause of bowel obstruction 13 years post-pancreas transplant. [PDF]

Front Transplant
Urvater M, Ianiro C, Bruce DS, Jensen T, Finger EB, Barr J.   +5 more
europepmc   +1 more source

Interpretable machine learning enables early and accurate detection of drug‐induced liver injury: A multicenter study with real‐world clinical translation

Interdisciplinary Medicine, EarlyView.
This study develops an interpretable gradient‐boosting model that accurately identifies drug‐induced liver injury (DILI) using routine laboratory data. The model explains key clinical features through SHapley Additive exPlanations analysis and detects DILI earlier than expert evaluation, offering a transparent and practical tool for precision ...
Jingyi Ling, Shian Zhang, Jun Lin, Zhengju Xu, Runcheng Xu, Qian Lv, Kaixiang Zhang, Sheng Liu, Jie Guo, Cheng Hua, Yin Jia, Xiaoyu Xu, Kun Qian, Shanrong Liu   +13 more
wiley   +1 more source

Glucose control during 3-month treatment with bihormonal artificial pancreas versus current diabetes care in patients after total pancreatectomy: study protocol for the PANORAMA randomized crossover trial. [PDF]

BJS Open
Leseman CA, van Veldhuisen CL, Rompen IF, Bouwense SA, Bosscha K, Busch OR, Dijkgraaf MGW, van Eijck CHJ, de Haan JS, Haen R, de Hingh IHJ, de Meijer V, Nijkamp MW, Mieog JSD, Molenaar IQ, van Santvoort HC, Stommel MWJ, Voermans RP, Wilmink JW, De Vries JH, Besselink MG.   +20 more
europepmc   +1 more source

Intratumoral bacteria engineered for tumor therapy

Interdisciplinary Medicine, EarlyView.
This article comprehensively reviews engineered intratumoral bacteria used in tumor therapy. The concept development, characteristics, and engineering methods of intratumoral bacteria are summarized. The mechanisms and the translational significance by which engineered intratumoral bacteria interfere with tumor progression are discussed and highlighted.
Huajie Zhang, Zelin Chen, Zeyu Yao, Sishi Luo, Cheng Luo, Rui Yang, Hao Fu, Songyin Huang   +7 more
wiley   +1 more source

Cellular Responses to Tartrazine and Sulfanilic Acid Exposure in BEAS‐2B Cells: Viability, Apoptosis, and DNA Damage

Journal of Applied Toxicology, EarlyView.
ABSTRACT Tartrazine is a synthetic azo dye widely used in food, pharmaceutical, and cosmetic products, resulting in extensive human exposure, while its toxicity and that of its primary metabolite, sulfanilic acid, remain controversial. Considering the reported association of tartrazine with hypersensitivity and allergic‐like reactions, human bronchial ...
Merve Baysal, Abdullah Burak Karaduman, Büşra Korkut Çelikateş, Merve Güven, Özlem Atlı‐Eklioğlu, Sinem Ilgın   +5 more
wiley   +1 more source