Results 81 to 90 of about 21,039,439 (231)

Structural Modifications of Nonsteroidal Anti‐Inflammatory Drugs (NSAIDs): New Horizons in Antimicrobial Drug Discovery

open access: yesArchiv der Pharmazie, Volume 359, Issue 8, August 2026.
This review provides a comprehensive analysis of the molecular modifications applied to NSAIDs to develop novel antimicrobial agents. By focusing on structural changes and their impact on biological activity, the study highlights innovative strategies to combat the global challenge of antimicrobial resistance.
Ebru Koçak Aslan   +2 more
wiley   +1 more source

Increasing the reporting of adverse drug reaction‐related hospitalizations using an ICD‐10‐based identification workflow: A multicentre study from Switzerland

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 8, Page 2937-2948, August 2026.
Background Reporting adverse drug reactions (ADRs) is essential for drug safety. In Switzerland, healthcare professionals are legally required to report serious and unlabelled ADRs, yet under‐reporting remains widespread. We tested a novel method to increase reporting of ADR‐related hospitalizations.
Georgia Anita Weber   +7 more
wiley   +1 more source

Gold nanoparticles/tetraaminophenyl porphyrin functionalized multiwalled carbon nanotubes nanocomposites modified glassy carbon electrode for the simultaneous determination of p-acetaminophen and p-aminophenol

open access: yes, 2017
A novel electrochemical platform was designed and prepared for simultaneous determination of p-acetaminophen (AMP) and p-aminophenol (AP) by combining the excellent conductivity and electrocatalytic activities of tetraaminophenyl porphyrin functionalized
Peiling Shi   +11 more
semanticscholar   +1 more source

Gram‐Scale Synthesis of Perdeuterated Paracetamol

open access: yesJournal of Labelled Compounds and Radiopharmaceuticals, Volume 69, Issue 10-11, August‐September 2026.
We report the synthesis of perdeuterated paracetamol on a multigram scale with an average deuterium incorporation of > 93% and no less than 78% at any individual position. ABSTRACT The synthesis of deuterated compounds is a major stumbling block in the field of neutron total scattering on disordered materials.
Alexander Park   +5 more
wiley   +1 more source

Investigate the Effects of Sonication on the Nucleation of Acetaminophen and Design the Sonoseeding Approach for Crystal Size Modification

open access: yesSolids
This study developed a sonoseeding strategy for controlling the crystal size of acetaminophen during cooling crystallization by introducing sonication into a supersaturated solution, thereby inducing nucleation.
Syuan Chen   +2 more
doaj   +1 more source

Multitarget Molecular Hybrids of Cinnamic Acids

open access: yesMolecules, 2014
In an attempt to synthesize potential new multitarget agents, 11 novel hybrids incorporating cinnamic acids and paracetamol, 4-/7-hydroxycoumarin, benzocaine, p-aminophenol and m-aminophenol were synthesized.
Aikaterini Peperidou   +3 more
doaj   +1 more source

Could NAPQI Contribute to Paracetamol Analgesia? Redox Modulation of Kv7 Ion Channels

open access: yesPharmacology Research &Perspectives, Volume 14, Issue 4, August 2026.
ABSTRACT Paracetamol (acetaminophen, APAP) is one of the most widely used analgesic and antipyretic drugs worldwide, yet its mechanism of action remains incompletely understood. While several pathways have been proposed, including cyclooxygenase inhibition and endocannabinoid modulation via AM404, none fully account for its pharmacological profile. The
Sara M‐Alicante   +6 more
wiley   +1 more source

Electron‐Donating Multifunctional Molecules: A Strategy for High‐Performance Perovskite Solar Cells

open access: yesRare Metals, Volume 45, Issue 8, August 2026.
ABSTRACT Multifunctional molecules containing electron‐donating groups are critically important in perovskite solar cells (PSCs), including defect passivation, crystallization modulation, energy level alignment, and other functions. This review systematically examines the application and research progress of such multifunctional molecules in PSCs ...
Heng Liu   +14 more
wiley   +1 more source

Cysteine conjugates of acetaminophen and p-aminophenol are potent inducers of cellular impairment in human proximal tubular kidney HK-2 cells. [PDF]

open access: yesArch Toxicol, 2023
Rousar T   +10 more
europepmc   +1 more source

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