Results 91 to 100 of about 18,720,874 (304)
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Composite reliability and convergent validity.
Composite reliability and convergent validity.
Isha Garg (14608681) +2 more
core +1 more source
Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee +6 more
wiley +1 more source
Composite reliability and convergent validity.
Composite reliability and convergent validity.
Syed Sohaib Zubair (11785527) +2 more
core +1 more source
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong +3 more
wiley +1 more source
Convergent multiples of convergent operators
Let “X≫0” mean that “the bounded linear Hilbert-space operator X is selfadjoint, positive, and invertible”. We discuss the operators A which are known to be convergent (i.e. have spectral radius less than 1) because they all satisfy Stein's condition P−A∗
Bryan E. Cain, Cain, Bryan E.
core +1 more source
Results of convergent factor loading.
Results of convergent factor loading.
Yongyi Chen (8261175) +2 more
core +1 more source
Rate of P-convergence over equivalence classes of double sequence spaces
This paper presents multidimensional characterizations of equivalence classes of double sequences. These characterizations will be analyzed by presenting theorems of the following type: If A is convergent preserving over \({\{x \in S^{\prime\prime}_{0} : x \;{\rm equivalent \; to}\; b\}}\) then there exists a \({b^{\prime} \in S^{\prime\prime}_{0 ...
Patterson, Richard F., Savas, Ekrem
openaire +4 more sources
Directed evolution of enzymes at the crossroads of tradition and innovation
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source

