Results 101 to 110 of about 25,735,174 (302)

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

Molecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh, Ji Yun Jang, Yoon Jeon, Gi‐Cheon Kim, Hwanho Lee, Jooyoung Lee, Ju‐Hwa Kim, Hakhyun Kim, Minjee Kim, Ho‐Keun Kwon, Ho Lee, Hyun Seok Kim   +11 more
wiley   +1 more source

On strong N?p(?)-convergence and S? (?) ?convergence

, 2021
In this paper, we introduce the concept of strong ??convergence of order ? ( or N? p (?) ?convergence ) of sequence of real numbers and give some inclusion relations between the set of all ??statistical convergence of order ? and strong N? p (?)-convergence.
Şengül Kandemir, Hacer, Et, Mikail
openaire   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Weakly and weak* p-convergent operators

Filomat
Let p ? [1, ?]. Being motivated by weakly p-convergent and weak* p-convergent operators between Banach spaces introduced by Fourie and Zeekoei, we introduce and study the classes of weakly p-convergent and weak* p-convergent operators between arbitrary locally convex spaces.
openaire   +1 more source

Factor loading, reliability, and convergent validity.

, 2023
Factor loading, reliability, and convergent validity.
Shahzaf Iqbal (15286036), Tahir Ashfaq (15286039), Che Azlan Bin Taib (15286042), Mohd Rizal Razalli (15286045)   +3 more
core   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

A preliminary validation of the impact on participation and autonomy questionnaire in an Iranian sample of patients with type 2 diabetes

Journal of Education and Health Promotion
BACKGROUND: This study aimed to determine the face, convergent validity, internal consistency, and stability reliability of the impact on participation and autonomy-Persian version (IPA-p) scale for using among Iranian patients with type 2 diabetes ...
Reza Vazirinejad, Mohammad Ali Zakeri, Hassan Ahmadinia, Sayed Mortaza Hossini Rafsanjanipoor   +3 more
doaj   +1 more source

Intraclass reliability for assessing how well Taiwan constrained hospital-provided medical services using statistical process control chart techniques

BMC Medical Research Methodology, 2012
Background Few studies discuss the indicators used to assess the effect on cost containment in healthcare across hospitals in a single-payer national healthcare system with constrained medical resources. We present the intraclass correlation coefficient (
Chien Tsair-Wei, Chou Ming-Ting, Wang Wen-Chung, Tsai Li-Shu, Lin Weir-Sen   +4 more
doaj   +1 more source

Some applications of uniformly $ p $-convergent sets

, 2020
arXiv admin note: text overlap with arXiv:1912.12454, arXiv:2002 ...
openaire   +2 more sources

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source