Results 51 to 60 of about 163,818 (266)

Measuring Quality of Life in Hidradenitis Suppurativa: Development and Validation of a Disease-specific Patient-reported Outcome Measure for Practice and Research

open access: yesActa Dermato-Venereologica, 2023
Hidradenitis suppurativa is a chronic disease that disrupts patients’ physical and psychological well-being. A disease-specific measure was developed and validated for assessing health-related quality of life in hidradenitis suppurativa.
Marina Otten   +10 more
doaj   +1 more source

On Double Statistical -Convergence of Fuzzy Numbers

open access: yesJournal of Inequalities and Applications, 2009
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Savaş, Ekrem, Patterson, Richard F.
openaire   +3 more sources

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Some fixed point results in fuzzy metric spaces using a control function [PDF]

open access: yesSurveys in Mathematics and its Applications, 2017
In this paper, we establish the results on existence and uniqueness of fixed point for φ-contractive and generalized C-contractive mapping in the fuzzy metric space in the sense of George and Veeramani.
C. T. Aage   +2 more
doaj  

Expressing functional siRNAs in mammalian cells using convergent transcription

open access: yesBMC Biotechnology, 2003
Background The use of small interfering RNAs (siRNAs) as genetic inhibitors of gene expression has been shown to be an effective way of studying gene function in mammalian cells.
Dawes Ian W   +3 more
doaj   +1 more source

Lacunary statistical convergence of double sequences [PDF]

open access: yes, 2005
In 1978 Freedman, Sember, and Raphael presented a definition for lacunary refinement as follows: $rho={bar{k}_{r}}$ is called a lacunary refinement of the lacunary sequence $theta ={k_{r}}$ if ${k_{r}}subseteq {bar{k}_{r}}$.
E. Savaş, R. F. Patterson
core  

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

$$L^p$$-convergence rate of backward Euler schemes for monotone SDEs

open access: yesBIT Numerical Mathematics, 2022
We give a unified method to derive the strong convergence rate of the backward Euler scheme for monotone SDEs in $L^p(Ω)$-norm, with general $p \ge 4$. The results are applied to the backward Euler scheme of SODEs with polynomial growth coefficients. We also generalize the argument to the Galerkin-based backward Euler scheme of SPDEs with polynomial ...
openaire   +2 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Static properties of nuclear matter within the Boson Loop Expansion

open access: yes, 2007
The use of the Boson Loop Expansion is proposed for investigating the static properties of nuclear matter. We explicitly consider a schematic dynamical model in which nucleons interact with the scalar-isoscalar sigma meson.
Alberico   +39 more
core   +1 more source

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