Results 61 to 70 of about 171,149 (281)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

A Quadratically Convergent Interior-Point Algorithm for the P*(κ)-Matrix Horizontal Linear Complementarity Problem [PDF]

open access: yesJournal of Sciences, Islamic Republic of Iran, 2012
In this paper, we present a new path-following interior-point algorithm for -horizontal linear complementarity problems (HLCPs). The algorithm uses only full-Newton steps which has the advantage that no line searchs are needed.
H. Mansouri
doaj  

Some applications of uniformly $ p $-convergent sets

open access: yes, 2020
arXiv admin note: text overlap with arXiv:1912.12454, arXiv:2002 ...
openaire   +2 more sources

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

A study on Copson operator and its associated sequence space II

open access: yesJournal of Inequalities and Applications, 2020
In this paper, we investigate some properties of the domains c ( C n ) $c(C^{n})$ , c 0 ( C n ) $c_{0}(C^{n})$ , and ℓ p ( C n ) $\ell _{p}(C^{n})$ ( 0 < p < 1 ) $(0 ...
Hadi Roopaei
doaj   +1 more source

The Relationship between Learning Styles (Convergent and Divergent) and the Effect of Random and Blocked Practices on the Learning of Badminton Serve Skills [PDF]

open access: yesرشد و یادگیری حرکتی ورزشی, 2015
The present study aimed at determining the relationship between learning styles and the effect of random and blocked practices on learning of badminton serve skills.
Mohammad Taghi Aghdasi, Sima Abdolzadeh
doaj   +1 more source

Fixed Points of Integral Type Contractions in Uniform Spaces with a Graph [PDF]

open access: yes, 2013
In this paper, we discuss the existence of fixed points for integral type contractions in uniform spaces endowed with both a graph and an $E$-distance. We also give two sufficient conditions under which the fixed point is unique.
Aghanians, Aris, Nourouzi, Kourosh
core  

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

An approach to validation of a multidimensional tool

open access: yesJournal of the College of Community Physicians, 2003
IntroductionShort Form Health Survey-36 (SF-36) is a multidimensional measure of general health which has been used extensively in research on many population groups.
N. S. Gunawardena   +2 more
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

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