Results 61 to 70 of about 177,357 (261)
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
A Note on Convergence Analysis of an SQP-Type Method for Nonlinear Semidefinite Programming
Journal of Inequalities and Applications, 2008 We reinvestigate the convergence properties of the SQP-type method for solving nonlinear semidefinite programming problems studied by Correa and Ramirez (2004).
Zhang Shaowu, Wang Yun, Zhang Liwei
doaj
Validation of WHOQOL-BREF to measure quality of life among women with polycystic ovary syndrome
Journal of the College of Community Physicians, 2006 IntroductionSymptoms typically associated with polycystic ovary syndrome (PCOS) such as oligo/ amenorrhoea, hirsutism, obesity, subfamily lead to a significant reduction in quality of life (QOL).
V. Kumarapeli +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Rate of P-convergence over equivalence classes of double sequence spaces
Positivity, 2011 This paper presents multidimensional characterizations of equivalence classes of double sequences. These characterizations will be analyzed by presenting theorems of the following type: If A is convergent preserving over \({\{x \in S^{\prime\prime}_{0} : x \;{\rm equivalent \; to}\; b\}}\) then there exists a \({b^{\prime} \in S^{\prime\prime}_{0 ...
Patterson, Richard F., Savas, Ekrem
openaire +4 more sources
Astrocyte heterogeneity in brain metastases
Molecular Oncology, EarlyView.Astrocytes emerge as pivotal regulators of metastatic colonization, survival, immune remodeling, and therapy response associated with an increasing heterogeneity that requires spatially and longitudinally resolved approaches to uncover regulatory programs and guide context‐specific therapies.
Carolina Hernández‐Oliver +2 more
wiley +1 more source
BMC Medical Research Methodology, 2012 Background Few studies discuss the indicators used to assess the effect on cost containment in healthcare across hospitals in a single-payer national healthcare system with constrained medical resources. We present the intraclass correlation coefficient (
Chien Tsair-Wei +4 more
doaj +1 more source