Results 61 to 70 of about 24,286,688 (300)
Expressing functional siRNAs in mammalian cells using convergent transcription
BMC Biotechnology, 2003 Background The use of small interfering RNAs (siRNAs) as genetic inhibitors of gene expression has been shown to be an effective way of studying gene function in mammalian cells.
Dawes Ian W +3 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Journal of NeuroEngineering and Rehabilitation, 2009 Background Spasticity is a common impairment accompanying stroke. Spasticity of the quadriceps femoris muscle can be quantified using the pendulum test.
Harrison Steven +2 more
doaj +1 more source
Matrix summability of statistically p-convergence sequences
Filomat, 2011 Matrix summability is arguable the most important tool used to characterize sequence spaces. In 1993 Kolk presented such a characterization for statistically convergent sequence space using nonnegative regular matrix. The goal of this paper is extended Kolk?s results to double sequence spaces via four dimensional matrix transformation.
Patterson, Richard F., Savaş, Ekrem
openaire +2 more sources
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Acta Dermato-Venereologica, 2023 Hidradenitis suppurativa is a chronic disease that disrupts patients’ physical and psychological well-being. A disease-specific measure was developed and validated for assessing health-related quality of life in hidradenitis suppurativa.
Marina Otten +10 more
doaj +1 more source
Statistical $p$-convergence in lattice-normed Riesz spaces
, 2022 A sequence $(x_n)$ in a lattice-normed space $(X,p,E)$ is statistical $p$-convergent to $x\in X$ if there exists a statistical $p$-decreasing sequence $q\stpd 0$ with an index set $K$ such that $δ(K)=1$ and $p(x_{n_k}-x)\leq q_{n_k}$ for every $n_k\in K$.
Aydın, Abdullah +2 more
openaire +2 more sources
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
The convergent media policy moment [PDF]
, 2012 This paper will consider some of the wider contextual and policy questions arising out of four major public inquiries that took place in Australia over 2011–2012: the Convergence Review, the National Classification Scheme Review, the Independent ...
Terry Flew
core
Convergent multiples of convergent operators [PDF]
, 1999 Let “X≫0” mean that “the bounded linear Hilbert-space operator X is selfadjoint, positive, and invertible”. We discuss the operators A which are known to be convergent (i.e. have spectral radius less than 1) because they all satisfy Stein's condition P−A∗
Bryan E. Cain, Cain, Bryan E.
core +1 more source