Perinatal exposure to the autism-linked metabolite p-Cresol has limited impact on early development in mice but lasting effects on adult social behavior [PDF]
Scientific ReportsEnvironmental exposures during pregnancy are increasingly recognized as significant risk factors for the offspring health. Perinatal exposure to environmental toxins, including p-Cresol, may disrupt essential physiological processes during critical ...
Juliette Canaguier +7 more
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Microbial and metabolic basis of p-cresol formation in fermented bamboo shoots (suansun): The central role of Levilactobacillus zymae KUST4216 [PDF]
Food Chemistry: Xp-Cresol plays a pivotal role in shaping the flavor quality of suansun. This study examined the effect of inoculating Levilactobacillus zymae KUST4216, a high p-cresol-producing strain, on the fermentation of suansun.
Zi Ye +7 more
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P-cresol Alters Brain Dopamine Metabolism and Exacerbates Autism-Like Behaviors in the BTBR Mouse [PDF]
Brain Sciences, 2020 Background: Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder characterized by deficits in social interaction/communication, stereotypic behaviors, restricted interests, and abnormal sensory-processing.
Tiziana Pascucci +8 more
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Optimization of Pyrocatechol and p-Cresol adsorption onto a composite of Chitosan and polyacrylamide incorporated with zeolitic imidazolate Framework-8 [PDF]
Scientific ReportsThe objective of the current research was to adsorb pyrocatechol and p-cresol from a water-based solution using CS-PAA-ZIF-8. Response surface methodology (RSM) using central composite design (CCD) was utilized to examine and optimize the process ...
Chou-Yi Hsu +9 more
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Recognition of the microbial metabolite p-cresol in autism spectrum disorder: systematic review and meta-analysis [PDF]
Frontiers in Molecular NeuroscienceIntroductionIn recent years, research has focused on the gut-brain axis and its microbial metabolites as potential etiological or physiopathological agents of autism spectrum disorders (ASDs). Elevated levels of the organic compound para-cresol (p-cresol)
María Isabel Serrano-Tomás +10 more
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Effect Produced by a Mixture of Phenol, p-Cresol, and Acetophenone on Four Species of Microalgae: Tolerance, Biodegradation, and Metabolic Alterations [PDF]
ToxicsPhenol-derived compounds are among the most hazardous organic pollutants for aquatic environments due to their relatively high aqueous solubility. Microalgae harbor metabolic pathways that enable the degradation of phenolic compounds into less toxic ...
Juan Manuel Rastrojo-Velasco +5 more
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Physicochemical data of p-cresol, butyric acid, and ammonia
Data in Brief, 2019 There is a renewed interest in treating odorous contaminants such as butyric acid, p-cresol, and ammonia that are emitted from animal farming operations.
Praveen Kolar +2 more
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Frontiers in Cellular and Infection Microbiology, 2021 Clostridioides difficile is the leading cause of antibiotic-associated diarrhea and is capable of causing severe symptoms, such as pseudomembranous colitis and toxic megacolon. An unusual feature of C.
Mark A. Harrison +3 more
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Bioenergetic strategy for the biodegradation of p-cresol by the unicellular green alga Scenedesmus obliquus. [PDF]
PLoS ONE, 2012 Cultures from the unicellular green alga Scenedesmus obliquus biodegrade the toxic p-cresol (4-methylphenol) and use it as alternative carbon/energy source. The biodegradation procedure of p-cresol seems to be a two-step process.
Aikaterini Papazi +2 more
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p-Cresol affects reactive oxygen species generation, cell cycle arrest, cytotoxicity and inflammation/atherosclerosis-related modulators production in endothelial cells and mononuclear cells. [PDF]
PLoS ONE, 2014 AIMS: Cresols are present in antiseptics, coal tar, some resins, pesticides, and industrial solvents. Cresol intoxication leads to hepatic injury due to coagulopathy as well as disturbance of hepatic circulation in fatal cases.
Mei-Chi Chang +9 more
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