Results 81 to 90 of about 20,206,431 (253)

p-Cresol induces disruption of cardiomyocyte adherens junctions

open access: yesToxicology, 2013
Higher serum levels of p-cresol in chronic kidney disease populations have been associated with increased cardiovascular mortality. However, studies on how p-cresol affects intercellular junctions between cardiomyocytes were limited. This study investigated the effect of p-cresol on adherens junction (AJ) of neonatal cultured cardiomyocytes and its ...
Yu-Sen, Peng   +5 more
openaire   +2 more sources

Touch-stimulation increases host-seeking behavior in Steinernema Carpocapsae. [PDF]

open access: yes, 2019
Previous research demonstrated that Steinernema carpocapsae infective juveniles (IJs) exposed to a host cuticle were more attracted toward certain host-associated volatile odors.
Baiocchi, Tiffany   +2 more
core  

Labeless and reversible immunosensor assay based upon an electrochemical current-transient protocol [PDF]

open access: yes, 2003
A novel labeless and reversible immunoassay based upon an electrochemical current-transient protocol is reported which offers many advantages in comparison to classical immuno-biochemical analyses in terms of simplicity, speed of response, reusability
Davis, Frank   +5 more
core   +1 more source

Pss knockdown in the midgut causes growth retardation in Drosophila similar to that in human LMHD

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Phosphatidylserine synthase (PSS), localized in the mitochondrial membrane, synthesizes phosphatidylserine. In humans, mutations in Pss lead to Lenz–Majewski hyperostotic dwarfism, a disorder affecting growth and development. The effects of Pss mutations on the growth of Drosophila melanogaster are not fully known. Hence, this study
Kwan‐Young Kim   +4 more
wiley   +1 more source

Unexpected transformation of dissolved phenols to toxic dicarbonyls by hydroxyl radicals and UV light. [PDF]

open access: yes, 2018
Water treatment systems frequently use strong oxidants or UV light to degrade chemicals that pose human health risks. Unfortunately, these treatments can result in the unintended transformation of organic contaminants into toxic products.
Ford, Breanna   +3 more
core   +1 more source

MiR‐30a‐5p mediates epileptogenesis in epilepsy models by targeting SOX4 to regulate the Wnt/β‐catenin pathway

open access: yesEpilepsia Open, EarlyView.
Abstract Objective The pathogenesis of epilepsy is closely associated with neuronal synaptic plasticity. MicroRNAs (miRNAs) can regulate various biological processes by binding to specific sequences on target genes. This study employs bioinformatics, molecular dynamics, and experimental approaches to investigate the mechanism by which MiR‐30a‐5p treats
Zhenlin Yang   +4 more
wiley   +1 more source

Removal of p-cresol and tylosin from water using a novel composite of alginate, recycled MnO2 and activated carbon.

open access: yesJournal of Hazardous Materials, 2019
For sustainable production, there is an urgent need to minimize the adverse environmental impacts of swine farming, which is a major contributor of the pollutants p-cresol and tylosin.
Jaehong Shim   +5 more
semanticscholar   +1 more source

The role of peroxidase in the enzymatic oxidation of phenolic compounds to quinones from Luffa aegyptiaca (gourd) fruit juice

open access: yesGreen Chemistry Letters and Reviews, 2017
Luffa aegyptiaca fruit juice was used as a low purity source of enzyme, which contained peroxidase activity of 180 IU/mL. The results of UV/VIS and IR studies suggested that L.
Meera Yadav   +2 more
doaj   +1 more source

N-terminal modification of proteins with o-aminophenols. [PDF]

open access: yes, 2014
The synthetic modification of proteins plays an important role in chemical biology and biomaterials science. These fields provide a constant need for chemical tools that can introduce new functionality in specific locations on protein surfaces.
Francis, Matthew   +2 more
core   +1 more source

Construction of Chronic Kidney Disease Mouse Model Induced by Diets With Different Adenine Content

open access: yesFood Safety and Health, EarlyView.
By administering a 4 weeks adenine diet to C57BL/6J mice, we identified 0.2% adenine in purified feed as the optimal chronic kidney disease model. This model induces severe renal damage, gut dysbiosis, uremic toxin accumulation, and CKD mineral bone disorder, providing a clinically relevant platform for mechanistic and therapeutic studies.
Wanjun Liao   +8 more
wiley   +1 more source

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