Results 201 to 210 of about 507,211 (287)

Evolution of Multivalent Aptamer Corona for High‐Throughput Multiplexed Detection of Multiple Cancers

Advanced Science, EarlyView.
A multivalent aptamer corona is evolved via established ProteoFish‐SELEX (systematic evolution of ligands by exponential enrichment) for high‐throughput multiplexed detection of multiple cancers. Clinical validation using multivalent aptamer corona demonstrated high accuracy and specificity in multiplexed detection of ovarian, lung, and colorectal ...
Mengjie Wang, Baichuan Jin, Xin Dai, Haozhe Huang, Qiqi Liu, Jianqing Zhu, Haixing Ju, Qixun Chen, Yongmei Song, Weihong Tan, Yuan Liu   +10 more
wiley   +1 more source

An immunohistochemical analysis of P-glycoprotein in retinoblastoma

Oman Journal of Ophthalmology, 2012
Sumita Sethi, Parul Saxena, Seema Kashyap, Neelam Pushker, Jasbir Kaur, Supriyo Ghose   +5 more
doaj   +1 more source

Navigating the blood-brain barrier to blood-brain tumor barrier transition: microvascular P-glycoprotein and CD146 potentially contribute to glioma grading. [PDF]

Fluids Barriers CNS
Mora A, Girolamo F, Marzullo A, Annese T, De Giorgis M, Signorelli F, Messina R, Ingravallo G, Virgintino D, Errede M, d'Amati A.   +10 more
europepmc   +1 more source

Pharmacokinetic Compatibility of Ginsenosides and Schisandra Lignans in Shengmai-san: From the Perspective of P-Glycoprotein

, 2014
Yan Liang, Yuanyuan Zhou, Jingwei Zhang, Tai Rao, Lijun Zhou, Xing Rong, Qian Wang, Hanxu Fu, Kun Hao, Lin Xie, Guangji Wang   +10 more
openalex   +2 more sources

Advanced Human Immune Cell‐Organoid Co‐Cultures for Functional Testing of Cancer Nanovaccines

Advanced Science, EarlyView.
Pancreatic ductal adenocarcinoma remains difficult to treat. We establish an organoid–immune co‐culture using patient‐derived organoids and matched T‐cells to assess cancer vaccines. A mesothelin‐targeted nanovaccine activates antigen‐specific T‐cells, increases IFN‐γ, and targets MSLN+ organoids.
Nathalia Ferreira, David Agorku, Andre Rosa, Julia Roosz, Lena Christ, Nicole Anderle, Ajinkya Kulkarni, Abir Hussein, Sana S. Sayedipour, Omar F. Luna, Tobias Legler, Philipp Ströbel, Fernando Albericio, Luis Cruz, Phillipp Beckhove, Peter Loskill, Frauke Alves, M. Andrea Markus, Fernanda Ramos‐Gomes   +18 more
wiley   +1 more source

A robust and interpretable graph neural network-based protocol for predicting p-glycoprotein substrates. [PDF]

Brief Bioinform
Hsu KC, Wang PH, Su BH, Tseng YJ.
europepmc   +1 more source

Relationships between rhodamine 123 transport, cell volume, and ion-channel function of P-glycoprotein.

, 1994
Guillermo A. Altenberg, Carlos G. Vanoye, Ernest Han, Joachim W. Deitmer, Luis Reuss   +4 more
openalex   +1 more source

Elevator‐Like Hollow Channels in Porous Scaffolds Accelerate Vascularized Bone Regeneration via NETs‐Fibrin‐Mediated Macrophage Recruitment

Advanced Science, EarlyView.
This study demonstrates that how hollow‐channel scaffolds promote vascularized bone regeneration via an immunomodulatory mechanism. The channel structures facilitate the formation of a neutrophil extracellular traps‐fibrin scaffold that recruits vascular endothelial growth factor A (VEGF‐A)‐secreting M2 macrophages to drive angiogenesis. Combining this
Guifang Wang, Rongpu Liu, Huijing Ma, Shuhan Duan, Guangzheng Yang, LingXi Meng, Yuqin Qiao, Dongqiang Song, Wenjie Zhang   +8 more
wiley   +1 more source

Enhancement of doxorubicin efficacy by diosmetin through DNA damage accumulation and P-glycoprotein inhibition in breast cancer cells. [PDF]

Sci Rep
Michalczyk M, Humeniuk E, Kubik J, Adamczuk G, Michalczuk M, Madej-Czerwonka B, Czerwonka M, Korga-Plewko A.   +7 more
europepmc   +1 more source