Results 101 to 110 of about 18,975,653 (260)
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
Continuous projections onto ideal convergent sequences
, 2018 Let I⊆ P(ω) be a meager ideal. Then there are no continuous projections from l∞ onto the set of bounded sequences which are I-convergent to 0. In particular, it follows that the set of bounded sequences statistically convergent to 0 is not isomorphic to ...
Leonetti P
core +1 more source
Acute caffeine treatment protects the developing retina from ischemia‐induced cell death
FEBS Open Bio, EarlyView.Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento +6 more
wiley +1 more source
Popüler Kültür ve Müzikte Anlamın Kaybı
Akademik İncelemeler Dergisi, 2015 Avrupa’da 17. yüzyıldan itibaren başlayan ekonomik, toplumsal, siyasal ve sosyal alanda yaşanan köklü değişimlerin ifadesi olan modernite, zamanla tüm dünyayı etkisi altına almıştır. Pek çok alanla birlikte özellikle kültür anlayışı ve sanata yansımaları
Mehmet Birekul
doaj +1 more source
Ideal version of Egorov's theorem for analytic P-ideals
Journal of Mathematical Analysis and Applications, 2009 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +2 more sources
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
On z-Ideals and z ◦ -Ideals of Power Series Rings
Journal of Mathematical Extension, 2013 Let R be a commutative ring with identity and R[[x]] be the ring of formal power series with coefficients in R. In this article we consider sufficient conditions in order that P[[x]] is a minimal prime ideal of R[[x]] for every minimal prime ideal P ...
A. Rezaei Aliabad, R. Mohamadian
doaj
FEBS Open Bio, EarlyView.The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley +1 more source
Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids
FEBS Open Bio, EarlyView.Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão +3 more
wiley +1 more source