Results 81 to 90 of about 25,586,114 (298)

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

What is an attractive body? Using an interactive 3D program to create the ideal body for you and your partner [PDF]

, 2012
What is the ideal body size and shape that we want for ourselves and our partners? What are the important physical features in this ideal? And do both genders agree on what is an attractive body?
Martin J. Tovée, Tovée Martin J., Cornelissen, Piers, Piers L Cornelissen, Piers L. Cornelissen, Kara L. Crossley, Crossley Kara L., Martin J Tové, Crossley, Kara, Tovée, Martin, Cornelissen Piers L., Kara L Crossley, Martin J Tovée   +12 more
core   +1 more source

Ideal Gas Equation

, 2012
Knowledge about kinect energy; temperature, pressureThe following educational object presents the concepts of an ideal gas and how it can mathematically be described, It also presents the correlations that lead to the ideal gas equationEducação Superior::
Khan Academy
core   +2 more sources

An interpolative class of two-Lipschitz mappings of composition type

Applied General Topology
The paper deals with some further results concerning the class of two-Lipschitz operators. We prove first an isometric isomorphism identification of two-Lipschitz operators and Lipschitz operators.
Khaled Hamidi, Abdelhamid Tallab
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Construction of k-Hyperideals by P-Hyperoperations

Ratio Mathematica, 2005
In this note we present a method to construction new k-hyperideals from given k-ideals of a semiring R by using of the P-hyperoperations. Then we investigate the relationship between them.
H. Hedayati, R. Ameri
doaj  

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

FUZZY p-IDEALS OF BCI-ALGEBRAS WITH DEGREES IN THE INTERVAL (0, 1]

Communications of the Korean Mathematical Society, 2012
Abstract. The notion of an enlarged p-ideal and a fuzzy p-ideal in BCI-algebras with degree are introduced. Related properties of them are in-vestigated. 1. IntroductionThe concept of a fuzzy set is applied to generalize some of the basic conceptsof general topology ([1]).
Yun-Sun Hwang, Sun-Shin Ahn
openaire   +2 more sources

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

FEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source