Results 71 to 80 of about 18,984 (255)

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

On Orbits of Order Ideals of Minuscule Posets [PDF]

Discrete Mathematics & Theoretical Computer Science, 2013
An action on order ideals of posets considered by Fon-Der-Flaass is analyzed in the case of posets arising from minuscule representations of complex simple Lie algebras.
David B. Rush, Xiaolin Shi
doaj   +1 more source

Algorithms and computations for foldedness of P-ideals in BCI-algebras

Journal of Applied Logic, 2008
Connections between \(n\)-fold P-ideals and fuzzy point \(n\)-fold P-ideals of BCI-algebras are described. Short algorithms for computations of such ideals are presented.
Moutari, Salissou, Lele, Celestin, Ndeffo Mbah, M.L.   +2 more
openaire   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

Molecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad, Marie Austdal, Oddmund Nordgård, Gunnar Mellgren, Satu Oltedal, Marie L. Austbø, Ylva H. Vignes, Thomas Helland, Kristin Jonsdottir, Tone H. Lende, Emilius A. M. Janssen, Bjørnar Gilje, Kjersti Tjensvoll, PBCB study group, Gunnar Mellgren, Tone Hoel Lende, Anette Heie, Kristin Viste, Anita Røyneberg Alvheim, Emiel AM Janssen, Kristin Jonsdottir, Ann Cathrine Kroksveen, Thomas Helland, Einar Gudlaugsson, Oddmund Nordgård, Satu Oltedal, Kristin Løge Aanestad, Jan Terje Kvaløy, Kirsten Lode, Kari Britt Hagen, Marie Austdal, Ylva H. Vignes, Siri Tungland Sola, Nina Egeland Amundsen, Finn Magnus Eliassen, Emeritus Ernst A Lien   +35 more
wiley   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Gotzmann lexsegment ideals

Le Matematiche, 2008
In this paper we characterize the componentwise lexsegment ideals which are componentwise linear and the lexsegment ideals generated in one degree which are Gotzmann.
Anda Olteanu, Oana Olteanu, Loredana Sorrenti   +2 more
doaj  

A note on M-ideals in certain algebras of operators

International Journal of Mathematics and Mathematical Sciences, 2000
Let X=(∑n=1∞ℓ1n)p,   p>1. In this paper, we investigate M-ideals which are also ideals in L(X), the algebra of all bounded linear operators on X. We show that K(X), the ideal of compact operators on X is the only proper closed ideal in L(X) which is both
Chong-Man Cho, Woo Suk Roh
doaj   +1 more source

On Quasi-P-Almost Distributive Lattices

Discussiones Mathematicae - General Algebra and Applications, 2020
In this paper, the concept of quasi pseudo-complementation on an Almost Distributive Lattice (ADL) as a generalization of pseudo-complementation on an ADL is introduced and its properties are studied.
Bandaru Ravi Kumar, Rao G.C.
doaj   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source