Results 101 to 110 of about 1,604,213 (297)

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

open access: yesFEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini   +2 more
wiley   +1 more source

Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival

open access: yesFEBS Open Bio, EarlyView.
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel   +9 more
wiley   +1 more source

Changes in Spo0A~P pulsing frequency control biofilm matrix deactivation.

open access: yesPLoS Computational Biology
Under starvation conditions, B. subtilis survives by differentiating into one of two cell types: biofilm matrix-producing cells or sporulating cells. These two cell-differentiation pathways are activated by the same phosphorylated transcription factor ...
Cristina S D Palma   +3 more
doaj   +1 more source

A new kind of $A_{\p}$-matrix for mixed graphs

open access: yes
Nikiforov\cite{nikiforov2017merging} introduced the concept of the $A_{\p}$-matrix as a convex linear combination of a graph's adjacency matrix and its diagonal matrix of vertex degrees. In this paper, we introduce a new variant of the $A_{\p}$-matrix, which is a linear combination of the Hermitian adjacency matrix of the second kind, $H^{\om}$, and ...
Sharma, Piyush, Kumar, Ravinder
openaire   +2 more sources

The quark compound bag model and the Jaffe-low P-matrix

open access: yesPhysics Letters B, 1981
Abstract A model with coupled hadronic and quark compound bag (QCB) channels is considered providing a natural basis for the if P -matrix analysis of the Jaffe-Low type. The resulting dynamical equations explain quantitatively the occurrence of a strong repulsive core as due to wide QCB states and predict large admiture of QCB states in nuclei.
openaire   +1 more source

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

open access: yesFEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee   +3 more
wiley   +1 more source

Homologous expression and purification of human HAX‐1 for structural studies

open access: yesFEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

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