Results 91 to 100 of about 1,682,430 (291)
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Generalization of the space l(p) $l(p)$ derived by absolute Euler summability and matrix operators
Journal of Inequalities and Applications, 2018 The sequence space l(p) $l(p)$ having an important role in summability theory was defined and studied by Maddox (Q. J. Math. 18:345–355, 1967). In the present paper, we generalize the space l(p) $l(p)$ to the space |Eϕr|(p) $\vert E_{\phi }^{r} \vert (p)$
Fadime Gökçe, Mehmet Ali Sarıgöl
doaj +1 more source
Principal components analysis on audiograms from a hearing aid clinic [PDF]
, 2010 In this study we describe a Principal Components Analysis (PCA) of 11,462 audiograms recorded at the hearing aid clinic at James Cook University Hospital in Middlesbrough between 1992 and 2001.
Anwar, Naveed, Oakes, Michael
core
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Distribution of P2O5 between P-rich Phase and Matrix Phase in P-bearing Steelmaking Slag
High Temperature Materials and Processes, 2018 To recycle the phosphorus in P-bearing steelmaking slag and use the slag as phosphate fertilizer, it is necessary to study the distribution of P2O5 between the P-rich phase and matrix phase in P-bearing steelmaking slag.
Lin Lu +4 more
doaj +1 more source
On the use of Fixed Trip Matrices for the Evaluation of Urban Highway Schemes [PDF]
, 1985 This paper begins with a summary of the theoretical background to the question of fixed or variable trip matrices and briefly reviews current UK advice and practice.
Bonsall, P.W.
core
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
The complex-type Pell p-numbers [PDF]
Notes on Number Theory and Discrete MathematicsIn this paper, we define the complex-type Pell p-numbers and give the generating matrix of these defined numbers. Then, we produce the combinatorial representation, the generating function, the exponential representation and the sums of the complex-type ...
Yeşim Aküzüm +2 more
doaj +1 more source
A Dantzig Selector Approach to Temporal Difference Learning
, 2012 LSTD is a popular algorithm for value function approximation. Whenever the number of features is larger than the number of samples, it must be paired with some form of regularization.
Geist, Matthieu +3 more
core +1 more source