Results 81 to 90 of about 28,541,050 (306)

Matrix spread sets of p-primitive semifield planes

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 1997
In this article we present the matrix spread sets of the p-primitive planes of order p4 where p=3,5,7,11.
M. Cordero
doaj   +1 more source

P-Matrix analysis of the dibaryon1 D 2 resonance

open access: yesZeitschrift für Physik C Particles and Fields, 1984
We study the relation between intermediate energy nucleon-nucleon scattering and the eigenstates of the bag model using theP-matrix formalism. Data of existing phase-shift analyses are employed to calculate theP-matrix for the coupled1D2(pp) and5S2(NΔ) channels in the energy region above the Δ-isobar production threshold. TheP-matrix calculated for the
I. L. Grach   +2 more
openaire   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

CNC–PNIPAM Drug Delivery System Improves Endometrial Receptivity via Natural Killer Cell Immune Tolerance in Endometriosis

open access: yesAdvanced NanoBiomed Research
Endometriosis (EM) results in pelvic adhesions and chronic inflammation, which significantly reduce embryo implantation and the clinical pregnancy rates of in vitro fertilization (IVF), affecting 190 million women worldwide.
Zhou Liang   +9 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

A novel approach to establishing uniqueness of solutions in linear complementarity problems

open access: yesMathematics Open
Linear complementarity problems are fundamental in various mathematical fields, and it is widely recognized that these problems have a unique solution if and only if the matrix related to them is a P-matrix.
Yamna Achik   +2 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

CLUSTERED MATRIX APPROXIMATION [PDF]

open access: yes, 2016
In this paper we develop a novel clustered matrix approximation framework, first showing the motivation behind our research. The proposed methods are particularly well suited for problems with large scale sparse matrices that represent graphs and/or ...
Dhillon, Inderjit S.,, Savas, Berkant,
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

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